Antimicrobial and anti-viral effects of selenium nanoparticles and selenoprotein based strategies: COVID-19 and beyond

Khurana, Amit; Allawadhi, Prince; Singh, Vishakha; Khurana, Isha; Yadav, Poonam; Sathua, Kshirod Bihari; Allwadhi, Sachin; Banothu, Anil Kumar; Navik, Umashanker; Bharani, Kala Kumar

doi:10.1016/j.jddst.2023.104663

Cited by 5 publications

(1 citation statement)

References 196 publications

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“…Having anti-inflammatory and antifibrotic effects, and a remarkable immunomodulatory effect, making them a suitable option for dietary supplements with a much lower toxicity risk, as well as direct antiviral properties, SeNPs can reveal new opportunities as suitable agents for this dangerous disease therapy and other viral infections with high mortality. They could be administered as an aerosol spray, a direct injection, or as thin-film transdermal patches to reduce the spread [283].…”

Section: Discussionmentioning

confidence: 99%

Selenium Nanoparticles: Green Synthesis and Biomedical Application

Mikhailova

2023

Molecules

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Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. “Green” synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. This review considers the biosynthesis mechanism of bacteria, fungi, algae, and plants, including the role of various biological substances in the processes of reducing selenium compounds to SeNPs and their further packaging. Modern information and approaches to the possible biomedical use of selenium nanoparticles are presented: antimicrobial, antiviral, anticancer, antioxidant, anti-inflammatory, and other properties, as well as the mechanisms of these processes, that have important potential therapeutic value.

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Section: Discussionmentioning

confidence: 99%