Antimicrobial and anti-biofilm activity of tannic acid against <i>Staphylococcus aureus</i>

Dong, Guofeng; Liu, Haiyang; X, Yu; Zhang, Xiaoxiao; Lu, Hong; Zhou, Tieli; Cao, Jianming

doi:10.1080/14786419.2017.1366485

Cited by 150 publications

(93 citation statements)

References 12 publications

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“…Tannic acid is a hydrolysable phenolic molecule, containing a central glucose unit and gallic acid esterified to it. The hydroxyl and carboxyl functional groups in TA allows for binding proteins and DNA, making TA an important candidate for antimicrobial and antifungal agents [ 22 , 23 ]. Chemopreventive and chemosensitization activity of TA has been demonstrated against several human carcinomas such as breast, ovarian and skin cancers [ 24 , 25 , 26 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

Tannic Acid Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Prostate Cancer

Nagesh

Hatami

Chowdhury

et al. 2018

Cancers

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Endoplasmic reticulum (ER) stress is an intriguing target with significant clinical importance in chemotherapy. Interference with ER functions can lead to the accumulation of unfolded proteins, as detected by transmembrane sensors that instigate the unfolded protein response (UPR). Therefore, controlling induced UPR via ER stress with natural compounds could be a novel therapeutic strategy for the management of prostate cancer. Tannic acid (a naturally occurring polyphenol) was used to examine the ER stress mediated UPR pathway in prostate cancer cells. Tannic acid treatment inhibited the growth, clonogenic, invasive, and migratory potential of prostate cancer cells. Tannic acid demonstrated activation of ER stress response (Protein kinase R-like endoplasmic reticulum kinase (PERK) and inositol requiring enzyme 1 (IRE1)) and altered its regulatory proteins (ATF4, Bip, and PDI) expression. Tannic acid treatment affirmed upregulation of apoptosis-associated markers (Bak, Bim, cleaved caspase 3, and cleaved PARP), while downregulation of pro-survival proteins (Bcl-2 and Bcl-xL). Tannic acid exhibited elevated G1 population, due to increase in p18INK4C and p21WAF1/CIP1 expression, while cyclin D1 expression was inhibited. Reduction of MMP2 and MMP9, and reinstated E-cadherin signifies the anti-metastatic potential of this compound. Altogether, these results demonstrate that tannic acid can promote apoptosis via the ER stress mediated UPR pathway, indicating a potential candidate for cancer treatment.

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Section: Introductionmentioning

confidence: 99%

Tannic Acid Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Prostate Cancer

Nagesh

Hatami

Chowdhury

et al. 2018

Cancers

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“…One solution to this potential problem is a modification of polymer hydrogels and fibers by microcontainers or microcapsules with, for example, tannic acid, which has antimicrobial properties. This would resist fibrosis and would improve angiogenesis of tissues [138,148,150,151]. It should be noted that signals generated by VEGF and TGF play an important role for proper regeneration of skin tissue and healing of wounds [144,147,152,153].…”

Section: Hybrid Biomaterials Applied For Skinmentioning

confidence: 99%

Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering

2020

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In this review, materials based on polymers and hybrids possessing both organic and inorganic contents for repairing or facilitating cell growth in tissue engineering are discussed. Pure polymer based biomaterials are predominantly used to target soft tissues. Stipulated by possibilities of tuning the composition and concentration of their inorganic content, hybrid materials allow to mimic properties of various types of harder tissues. That leads to the concept of "one-matches-all" referring to materials possessing the same polymeric base, but different inorganic content to enable tissue growth and repair, proliferation of cells, and the formation of the ECM (extra cellular matrix). Furthermore, adding drug delivery carriers to coatings and scaffolds designed with such materials brings additional functionality by encapsulating active molecules, antibacterial agents, and growth factors. We discuss here materials and methods of their assembly from a general perspective together with their applications in various tissue engineering sub-areas: interstitial, connective, vascular, nervous, visceral and musculoskeletal tissues. The overall aims of this review are two-fold: (a) to describe the needs and opportunities in the field of bio-medicine, which should be useful for material scientists, and (b) to present capabilities and resources available in the area of materials, which should be of interest for biologists and medical doctors.Polymers 2020, 12, 620 2 of 30 allows to tailor functionalize the coatings, where their responsiveness to external stimuli is one of their biggest advantages.Polymers stand out as a special class of materials due to the flexibility of design of their blocks and various functionalities, which is brought by their versatile assembly or by introducing additional side-groups or blocks, in the case of block-co-polymers. In this regard, both synthetic and biocompatible polymers are available, and polymer engineering represents a growing area tailoring the needs often driven by applications. With all advantages and the flexibility of the design, there is one significant weakness of polymers-the softness. In regard with tissue engineering, that translates to the fact that some materials can match predominantly soft tissue, but it is difficult to tune mechanical properties of polymers to match the hardness of bones, tendons, etc. And since mechanical properties of materials affect and even drive cell and tissue growth, enhancement of mechanical properties of polymers and biomaterials is essential. Chemical crosslinking can be applied to address these challenges, but that solves problems only partially.To solve these challenges the so-called hybrid materials [6] are used, which possess both inorganic and organic contents. Increasingly, hybrid materials are used in designing the extracellular matrix. The hybrid matrix design for various tissue engineering applications should meet bio-medical requirements. On the one hand, it needs to be biocompatible and biodegradable, which is achieved through the po...

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“…Many pharmaceutical based businesses have identified the role of plants in sourcing for pharmacological compounds because they have immense medicinal properties [3]; secondary metabolites that are of great importance include flavonoids, tannins, alkaloids, phenols, saponins, terpenoids and cardiac glycosides are from plants [4]. Each of the secondary metabolites possess explicit function such as antifungal action of saponin [5], antimicrobial activity of tannin [6], usefulness of certain alkaloids for the treatment of HIV infection [7], potent anti-cancer activity of flavonoids [8]. Medicinal plants extensively occur globally and now it's getting more consideration because they have several beneficial properties to all human beings especially in pharmacological and medicine field.…”

Section: Phytochemicalsmentioning

confidence: 99%

Phytochemical Status of Different Solvent Extracts of Anthocleista djalonensis A. Chev Leaves

Popoola

2019

Int. Ann. Sci.

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The choice of suitable solvent is essential in the extraction of much needed bioactive phytochemicals present in medicinal plants. This study assessed the phytochemical status of four solvents (methanol, hexane, ethylacetate and aqueous) extracts of Anthocleista djalonensis, leaves of the plants were extracted with the solvents by cold maceration for three days; screening and quantitative determination of saponin, alkaloid, tannin, cardiac glycosides, flavonoids phenols and terpenoids was done using standard methods. Phytochemical screening indicates the presence of all the phytocompound in the methanol extract, while other extracts shows variation in the availability of different phytochemicals, quantitative results shows alkaloid ranged from 1.79-18.90 mg/100g, flavonoids: 2.54-10.53 mg/100g, saponin: 2.00-12.23 mg/100g, tannin: ND-4.83 mg/100g, phenol: ND-6.65 mg/100g, cardiac glycoside: ND-2.08 mg/100g, and terpenoids: ND-1.98 mg/100g; significant difference (p<0.05) exist in each phytochemicals across the solvents where methanol and the aqueous extracts gave the best extraction efficiency for the phytochemicals. Consequently, the optimum extraction of useful phytochemicals from A. djalonensis could be achieved using either methanol and water.

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Antimicrobial and anti-biofilm activity of tannic acid against Staphylococcus aureus

Cited by 150 publications

References 12 publications

Tannic Acid Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Prostate Cancer

Tannic Acid Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Prostate Cancer

Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering

Phytochemical Status of Different Solvent Extracts of Anthocleista djalonensis A. Chev Leaves

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