Antimicrobial activity of varying concentrations of sodium hypochlorite on the endodontic microorganisms Actinomyces israelii, A. naeslundii, Candida albicans and Enterococcus faecalis

Radcliffe, Charlotte E.; Potouridou, L.; Qureshi, Rizwan; Habahbeh, N.; Qualtrough, A. J. E.; Worthington, Helen V; Drucker, D.B.

doi:10.1111/j.1365-2591.2004.00752.x

Cited by 209 publications

(181 citation statements)

References 37 publications

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“…Furthermore, there is evidence that hypochlorite is not effective against all pathogenic bacteria specifically Enterococcus faecalis which is associated with recalcitrant canals. 14 Further complications of conventional disinfecting agents are toxicity and microbial resistance [15][16][17] since most which have effective bactericidal activity are used at concentrations where normal tissue toxicity is becoming a significant factor. This can lead to adverse tissue reactions.…”

Section: Introductionmentioning

confidence: 99%

An alternative regimen for root canal disinfection

et al. 2006

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Objective To compare the effect of a combination of 20% citric acid solution and photo-activated disinfection with the use of 20% citric acid and 2.25% sodium hypochlorite solutions on bacterial load on the dentine walls in prepared canals in vivo. Subjects and methods Sixty-four randomly selected cases were evaluated and allocated to one of two groups. In Group 1, after gaining access to the root canal, bacterial load on the canal walls was sampled using endodontic files. A further sample was taken after apex location and initial widening of the canal had been completed and the photoactivated disinfection process carried out. A final sample was taken after completion of the canal preparation using citric acid and sodium hypochlorite solutions. In Group 2, the initial sample was taken as described previously. A second sample was taken after conventional preparation using 20% citric acid and sodium hypochlorite solutions as co-irrigants. A final sample was then taken after a subsequent PAD treatment. All samples were cultured for facultative anaerobic bacteria. Results Of the canals treated in Group 1 only two of the 23 canals infected showed culturable bacteria after the use of citric acid and photo-activated disinfection. Of these two canals, one was free of culturable bacteria on completion of conventional treatment but the other still contained culturable bacteria. In Group 2, four canals of the 23 infected initially, remained contaminated after conventional treatment. After subsequent photo-activated disinfection three of these four canals were free of culturable bacteria. Conclusion Results indicate that the use of a chelating agent acting as a cleaner and disrupter of the biofilm and photo-activated disinfection to kill bacteria is an effective alternative to the use of hypochlorite as a root canal cleaning system.

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Section: Introductionmentioning

confidence: 99%

An alternative regimen for root canal disinfection

et al. 2006

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“…Vianna et al (22) demonstrated that the time required by 1% NaOCl to eliminate suspensions of E. faecalis, S. aureus, and C. albicans was 20 minutes. Whereas Radcliffe et al (23) verified that the same concentration of irrigant required 10 minutes to promote negative cultures of suspensions of E. faecalis. However, Retamozo et al (24) observed that 1.3% NaOCl was not able to disinfect dentin cylinders contaminated with E. faecalis even after 40 minutes of irrigation.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Microbial Reduction in Root Canals Instrumented with Reciprocating and Rotary Systems

Oliveira

Aguiar

Câmara

et al. 2015

Acta Stomatol Croat

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“…14 However, it is relatively ineffective against Enterococcus faecalis, a root canal microorganism. 15 Sodium hypochlorite also has a high surface tension which prevents deeper penetration of the irrigant into dentinal tubules. 16 Increasing the temperature of the solution and the time that it is in contact with tissues in the root canal can increase cellular destruction.…”

Section: Root Canal Irrigantsmentioning

confidence: 99%