Antimicrobial activity of some Sri Lankan Rubiaceae and Meliaceae

Jayasinghe, U. L. B.; Jayasooriya, Champika P.; Bandara, B. M. Ratnayake; Ekanayake, S.; Merlini, Lucio; Assante, Gemma

doi:10.1016/s0367-326x(02)00122-3

Cited by 42 publications

(24 citation statements)

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“…However, some other Wendlandia sp. are used against dysentery, fever, diarrhea, ulcers, and rheumatism in Far Eastern countries (Jayasinghe et al, 2002). Several members of the genus Scrophularia find use as herbal remedy, both internally and externally, for their antiseptic and digestive properties (Sezik et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Biological Activity of Turkish Plants. Rapid Screening for the Antimicrobial, Antioxidant, and Acetylcholinesterase Inhibitory Potential by TLC Bioautographic Methods

Taşdemir

Dönmez

Çalış

et al. 2004

Pharmaceutical Biology

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Using thin-layer chromatography (TLC) bioautography, a total of 58 extracts from various organs (aerial parts, leaves, flowers, fruits, roots) of 16 Turkish plants were tested for their antibacterial, antifungal, acetylcholinesterase inhibitory, antioxidant, and radical scavenging activities. The hexane, CHCl 3 /CH 2 Cl 2 , water, and total MeOH extracts were used. No activity was observed against two Gram-negative bacteria (Escherichia coli and Pseudomonas aureginosa) and the yeast Candida albicans. However, 23 plant extracts, mostly the CHCl 3 /CH 2 Cl 2 and H 2 O-solubles, inhibited the growth of all five Gram-positive bacteria tested, Micrococcus luteus, Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, and Staphylococcus epidermidis. Of the active extracts, the CHCl 3 -soluble of the roots of Putoria calabrica (L. fil) DC (Rubiaceae) displayed the highest antibacterial potential. The majority of the CHCl 3 /CH 2 Cl 2 crude extracts also appeared to inhibit acetylcholinesterase on TLC plates at 100 mg/spot concentration. Particularly active samples were the middle polarity extracts (CHCl 3 /CH 2 Cl 2 ) of the leaves of Rhododendron smirnovii Trautv., R. ponticum L., and R. ungernii Trautv. (Ericaceae). b-Carotene, bcarotene/linoleic acid mixture, and 2,2-diphenyl-l-pieryhydrazyl (DPPH) solutions sprayed onto TLC plates were used for detecting antioxidant and radical scavenging properties of the crude extracts. Antioxidant and radical scavenging activities were found to be predominant in highly polar extracts. The water-solubles of all Rhododendron (Ericaceae) and Phlomis (Lamiaceae) species presented the most significant activity.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Biological Activity of Turkish Plants. Rapid Screening for the Antimicrobial, Antioxidant, and Acetylcholinesterase Inhibitory Potential by TLC Bioautographic Methods

Taşdemir

Dönmez

Çalış

et al. 2004

Pharmaceutical Biology

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“…Chomelia asiatica (Linn) is a common species which occurs in india, Srilanka and China. The leaves or powder extracts of C. asiatica are used as antimicrobial activities (Jayasinghe et al, 2002). It had been accounted for pain relieving and mitigating activities (Amutha et al, 2012).…”

Section: The Plant Materials (Study Species)mentioning

confidence: 99%

In vivo antioxidant and lipid peroxidation effect of various extracts from aerial parts of Chomelia asiatica (Linn) in rat fed with high fat diet

Thayyil¹,

Muthu²,

Ibrahim³

2016

Afr. J. Pharm. Pharmacol.

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The present investigation was to examine the in vivo antioxidant activity and lipid peroxidation activities of different extracts of aerial parts of Chomelia asiatica (Linn). High fat diet rats demonstrated fundamentally decreased the levels of tissues enzymatic antioxidant and non-enzymatic antioxidant (Glutathione). The level of thiobarbuturic acid reactive substance (TBARS) is reduced in high-fat diet (HFD) rats when compared and control group. Administration of ethyl acetate extract of Chomelia asiatica in high fat diet rats were indicated altogether (p<0.001) increased the levels of antioxidant enzymes, for example, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and level of non enzymatic antioxidant glutathione (GSH) when contrasted and HFD rats (Group II). The ethyl acetate extract of C. asiatica in high fat diet rats were discovered lowered the concentration of TBARS when contrasted and HFD rats. In comparison of all the three extracts treated group with standard group, the ethyl acetate extract of C. asiatica showed significant (p<0.001) result than that of other groups. Taking into account the outcomes, we concluded that the ethyl acetate extract of C. asiatica is a significant source of antioxidant, which may be useful in keeping the advancement of different oxidative stresses.

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“…The phytochemical constituents of it are reported to be antimicrobial (Jayasinghe et al, 2002;Rajakaruna et al, 2002;Ramabharahi et al, 2014), antiseptic (Vinothkumar et al, 2011), antiinflammatory (Amutha et al, 2012), wound healing (Anjanadevi and Menaga, 2013) and antioxidant (Ramabarathi et al, 2014). Besides, the extract of shoots, leaves and fruits are purportedly active against Mycobacter phlei (Rajakaruna et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

Antiviral activity of leaf-bud gum-resin of <i>Tarenna asiatica</i>

Ramabharathi¹,

Saigopal

Rajitha

2014

Bangladesh J Pharmacol

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The leaf-bud exudate of Tarenna asiatica (Rubiaceae: Ixoroideae, Pavetteae) is investigated for its biological activity. The crude benzene extract and corymbosin (pure compound isolated) were screened for antiviral activity by using ELISA and PCR methods against animal (blue tongue and chikungunya) and plant (papaya ring spot, sesbania mosaic and common bean mosaic) viruses. Both corymbosin and benzene extract showed significant antiviral activity though corymbosin was found relatively more potent against the animal and plant viruses tested. This is the first report of antiviral activity for the gumresin of T. asiatica, so also for the compound corymbosin, against the plant viruses. Article Info

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Antimicrobial activity of some Sri Lankan Rubiaceae and Meliaceae

Cited by 42 publications

References 0 publications

Evaluation of Biological Activity of Turkish Plants. Rapid Screening for the Antimicrobial, Antioxidant, and Acetylcholinesterase Inhibitory Potential by TLC Bioautographic Methods

Evaluation of Biological Activity of Turkish Plants. Rapid Screening for the Antimicrobial, Antioxidant, and Acetylcholinesterase Inhibitory Potential by TLC Bioautographic Methods

In vivo antioxidant and lipid peroxidation effect of various extracts from aerial parts of Chomelia asiatica (Linn) in rat fed with high fat diet

Antiviral activity of leaf-bud gum-resin of <i>Tarenna asiatica</i>

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