Antimicrobial activity of marine fungi isolated from the Son Tra peninsula, Da Nang, Vietnam

Trinh, Phan Thi Hoai; Ngoc, Ngo Thi Duy; Trang, Vo Thi Dieu; Phong, Le Quoc; Tien, Phi Quyet; Lý, Bùi Minh; Vân, Trần Thị Thanh

doi:10.15625/0866-7160/v39n4.8889

Cited by 2 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Differences in the ability of marine fungi to inhibit the growth of microbes may be reasoned by sensitivity to antimicrobial compounds contained in extracts. faecalis, L. monocytogenes, S. aureus, E. coli, C. albicans, and P. aeruginosa were 42, 33, 31, 22, 7, 5, and 3%, respectively [12]. Moreover, marine fungal strains isolated from sediments in Co To island -Quang Ninh Province also exhibited great antimicrobial activity against reference pathogens [13].…”

Section: Antibacterial Activity Of Isolated Marine Fungimentioning

confidence: 96%

“…VK12 was isolated from marine sponge collected from the Quang Nam sea and yielded compounds (3R)-(3,5-dihydroxy phenyl)butan-2-one and AGI-7 showed cytotoxicity toward HepG2, MCF-7, and SKMel2 carcinoma cells [11]. Due to the increasing demand for new antibiotics mechanism of action, antibacterial activity is one of the looks of the properties of marine fungi [12,13]. Besides, recent studies have confirmed marine fungi are a valuable source of antioxidant compounds with potent biological activity and various structural features, promising sources of novel bioactive compounds [14,15].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Screening of antibacterial and antioxidant activities of marine fungi isolated from the North Sea of Vietnam

Ngo,

Phan,

Dinh

et al. 2023

VJMST

View full text Add to dashboard Cite

Marine fungi are recognized as a rich source of pharmacologically active secondary metabolites, different from terrestrial fungi. This study aimed to assess the antimicrobial and antioxidant activities of 61 marine fungal strains isolated from 34 samples collected in the research journey of the Akademik Oparin vessel in the North Sea of Vietnam in 2021. Of these, 23 were from sponges, 21 from seaweeds, 15 from sediments, and only 2 from seawater. The antimicrobial screening results showed that 75.4% (n = 46) of fungal strains exhibited inhibitory activity against at least one test microorganism. The antioxidative properties results indicated the capacity for free DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging of crude extracts with 32.7% (n = 20) and 93.4% (n = 57), respectively. Six isolates with potent antibiotic and antioxidant activities were identified as belonging to the phylum Ascomycota and affiliated with five genera. Our findings indicated that these marine fungi could be impressive sources of multi-functional bioactive compounds and may find applications in the pharmaceutical industry.

show abstract

Section: Antibacterial Activity Of Isolated Marine Fungimentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Screening of antibacterial and antioxidant activities of marine fungi isolated from the North Sea of Vietnam

Ngo,

Phan,

Dinh

et al. 2023

VJMST

View full text Add to dashboard Cite

show abstract

“…2 New developments in discovery of drugs from natural sources highlight on exploration of the marine environment to discover various novel and complex secondary metabolites for management of several diseases such as inflammatory condition, AIDS, cancer, malaria, fungal and viral diseases. 3 Fungi produce a diversity of molecules with unique structures and display innumerable biological activities [4][5][6] including anticancer, antiinflammatory, antiviral and antimicrobial. Since the past era, the number of antifungal and antibacterial metabolites from marine fungi have a rapid growing, making marine fungi a considered potential sources for natural metabolites.…”

Section: Introductionmentioning

confidence: 99%

Optimization and Characterization of Antimicrobial Agents Produced by Marine Aspergillus terreus She05 against Aeromonas hydrophila and other Applications

Latif¹,

Hassan²,

Beltagy³

2021

J. Pure Appl. Microbiol.

View full text Add to dashboard Cite

Seven morphologically distinct marine fungi were isolated from sediment and Seawater samples at different sites along Alexandria seashore. Antagonism effect against Aeromonas hydrophila on purpose and other pathogen was estimated. The most promising isolate giving the highest antibacterial activity (14 mm) against A. hydrophila was morphologically and genetically identified as Aspergillus terreus SHE05 and the corresponding sequence was recorded in the GenBank database with accession no. MW772239. Time course production of the antibacterial agents by A. terreus SHE05 against A. hydrophila was studied showing the highest productivity after 5 days incubation. Multi-factorial design in terms of Placket Burman design was implemented to predict the critical factors influencing the production of the antibacterial agents by A. terreus SHE05 against A. hydrophila. The obtained results showed that malt extract, pH and temperature were the key factors affecting the antimicrobial activity. Consequently, Box-Behnken design was applied to estimate the optimized levels of each independent variable showing that the optimized conditions were malt extract, 3 (g/l); peptone, 0.75 (g/l); salinity, 50%; pH, 4; culture age, 4 days; inoculum size, 0.5 ml; temperature 30°C and incubation time 5 days, which caused an increase in the antimicrobial activity to 25 mm, which denotes an approximately 1.8 fold increase comparing with the pre-optimized conditions. The potentiality of chloroform, hexane, petroleum ether and ethyl acetate for extraction of the active compounds was tested showing that ethyl acetate was the best. The extracted bioactive metabolites using ethyl acetate were tested as antimicrobial, anticancer, antiviral and antioxidant agents. Results showed reasonable activities. GC-MS was used to recognize the active components in the ethyl acetate extract, showing that the major compound was the Dodecanamine, N,N-Dimethyl with RT 11.95, molecular weight 213, area % (55.46) and molecular formula C14H31N.

show abstract

Antimicrobial activity of marine fungi isolated from the Son Tra peninsula, Da Nang, Vietnam

Cited by 2 publications

References 13 publications

Screening of antibacterial and antioxidant activities of marine fungi isolated from the North Sea of Vietnam

Screening of antibacterial and antioxidant activities of marine fungi isolated from the North Sea of Vietnam

Optimization and Characterization of Antimicrobial Agents Produced by Marine Aspergillus terreus She05 against Aeromonas hydrophila and other Applications

Contact Info

Product

Resources

About