Antimicrobial Activity of Lemongrass Essential Oil (Cymbopogon flexuosus) and Its Active Component Citral Against Dual-Species Biofilms of Staphylococcus aureus and Candida Species

Gao, Shanjun; Liu, Guangzhi; Li, Jianguo; Chen, Jing; Li, Lina; Li, Zhen; Zhang, Xiulei; Zhang, Shoumin; Thorne, Rick F.; Zhang, Shuzhen

doi:10.3389/fcimb.2020.603858

Cited by 84 publications

(60 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In another study, the efficacy of lemongrass ( Cymbopogon flexuosus ) essential oil and its bioactive part citral against dual-species biofilms formed by Staphylococcus aureus and Candida species was evaluated in vitro [ 69 ]. Biofilm staining and viability tests showed both lemongrass essential oil and citral were able to reduce biofilm biomass and cell viability of each species in the biofilm.…”

Section: Bioactivitymentioning

confidence: 99%

Backhousia citriodora F. Muell. (Lemon Myrtle), an Unrivalled Source of Citral

Southwell

2021

Foods

View full text Add to dashboard Cite

Lemon oils are amongst the highest volume and most frequently traded of the flavor and fragrance essential oils. Citronellal and citral are considered the key components responsible for the lemon note with citral (neral + geranial) preferred. Of the myriad of sources of citral, the Australian myrtaceous tree, Lemon Myrtle, Backhousia citriodora F. Muell. (Myrtaceae), is considered superior. This review examines the history, the natural occurrence, the cultivation, the taxonomy, the chemistry, the biological activity, the toxicology, the standardisation and the commercialisation of Backhousia citriodora especially in relation to its essential oil.

show abstract

Section: Bioactivitymentioning

confidence: 99%

Backhousia citriodora F. Muell. (Lemon Myrtle), an Unrivalled Source of Citral

Southwell

2021

Foods

View full text Add to dashboard Cite

show abstract

“…S. aureus is a common gram-positive pathogenic bacterium with strong pathogenicity, which greatly threatens the health and even life of S. aureus-infected patients (Briaud et al, 2020;Gao et al, 2020). Early rapid diagnosis of S. aureus is valuable for the timely use of effective antimicrobial therapy to improve prognosis.…”

Section: Discussionmentioning

confidence: 99%

A New Optical Fiber Probe-Based Quantum Dots Immunofluorescence Biosensors in the Detection of Staphylococcus aureus

Cui

Zhou

Liu

et al. 2021

Front. Cell. Infect. Microbiol.

View full text Add to dashboard Cite

Staphylococcus aureus (S. aureus) is one of the most common clinical pathogenic bacteria with strong pathogenicity and usually leads to various suppurative infections with high fatality. Traditional bacterial culture for the detection of S. aureus is prone to diagnosis and antimicrobial treatment delays because of its long-time consumption and low sensitivity. In this study, we successfully developed a quantum dots immunofluorescence biosensor for S. aureus detection. The biosensor combined the advantages of biosensors with the high specificity of antigen-antibody immune interactions and the high sensitivity and stability of quantum dots fluorescence. The results demonstrated that the biosensor possessed high specificity and high sensitivity for S. aureus detection. The detection limit of S. aureus reached 1 × 104 CFU/ml or even 1 × 103 CFU/ml, and moreover, the fluorescence intensity had a significant positive linear correlation relationship with the logarithm of the S. aureus concentration in the range of 103–107 CFU/ml (correlation coefficient R2 = 0.9731, P = 0.011). A specificity experiment showed that this biosensor could effectively distinguish S. aureus (1 × 104 CFU/ml and above) from other common pathogenic (non-S. aureus) bacteria in nosocomial infections, such as Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii and Escherichia coli. Additionally, the whole detection procedure spent only 2 h. In addition, the biosensor in this study may not be affected by the interference of the biofilm or other secretions since the clinical biological specimens are need to be fully liquefied to digest and dissolve viscous secretions such as biofilms before the detection procedure of the biosensor in this study. In conclusion, the biosensor could meet the need for rapid and accurate S. aureus detection for clinical application.

show abstract

“…Recent decades mark an exponential upsurge in establishing the bioactivities of lemongrass extract and essential oil. Feeding studies establish that LEO has antimicrobial, anticancer, anti-amoebic, anti-diarrhoeal, anti-filarial, antitussive, antiseptic, larvicidal, insecticidal, miticidal, ovicidal, acaricidal, analgesic, anesthetic, anti-inflammatory, antioxidant, antinociceptive, antihypertensive, anti-obesity, anxiolytic, and antimutagenicity potential, cardio-protective, anti-rheumatic, and hematological properties [7,[17][18][19][20][21][22][23][24][25][26][27][28][29]. These bioactivities are the direct product of the individual and synergistic effect of different major and minor LEO components [11].…”

Section: Leo Therapeuticsmentioning

confidence: 99%

Lemongrass Essential Oil Components with Antimicrobial and Anticancer Activities

Mukarram¹,

Choudhary²,

Khan³

et al. 2021

Preprint

View full text Add to dashboard Cite

The prominent cultivation of lemongrass relies on the pharmacological incentives of its essential oil. The lemongrass essential oil (LEO) has a significant amount of citral (mixture of geranial and neral), isoneral, isogeranial, geraniol, geranyl acetate, citronellal, citronellol, germacrene-D, and elemol in addition to numerous other bioactive compounds. These components confer various medicinal activities to LEO including antifungal, antibacterial, antiviral, anticancer, and antioxidant properties. These attributes are commercially exploited in pharmaceutical, cosmetics, and food preservations industries. Furthermore, the employment of LEO in the treatment of cancer opens a new vista in the field of therapeutics. Although different LEO components have shown promising anticancer activities in vitro, these effects have not been assessed yet in humans. Further studies on the anticancer mechanisms exerted by lemongrass components are required. The present review intends to provide a timely discussion on the relevance of lemongrass extracts in cancer and health treatment, and in food industry applications.

show abstract

Antimicrobial Activity of Lemongrass Essential Oil (Cymbopogon flexuosus) and Its Active Component Citral Against Dual-Species Biofilms of Staphylococcus aureus and Candida Species

Cited by 84 publications

References 34 publications

Backhousia citriodora F. Muell. (Lemon Myrtle), an Unrivalled Source of Citral

Backhousia citriodora F. Muell. (Lemon Myrtle), an Unrivalled Source of Citral

A New Optical Fiber Probe-Based Quantum Dots Immunofluorescence Biosensors in the Detection of Staphylococcus aureus

Lemongrass Essential Oil Components with Antimicrobial and Anticancer Activities

Contact Info

Product

Resources

About