Antimicrobial Activity of Indigofera suffruticosa

Leite, Sônia Pereira; Vieira, Jeymesson Raphael Cardoso; Medeiros, Paloma Lys de; Leite, Roberta Maria Pereira; Lima, Vera Lúcia de Menezes; Xavier, Haroudo Sátiro; Lima, Edeltrudes de Oliveira

doi:10.1093/ecam/nel010

Cited by 57 publications

(54 citation statements)

References 26 publications

(20 reference statements)

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“…Although the activity was much lower as compared to the standard antibiotics, our results however confirm some activity in concurrence with those obtained by other researchers working on other Indigofera species (Leite et al, 2006;Dahot, 1999;Esimore et al, 1999). The results show that Gram positive bacteria i.e.…”

Section: Resultssupporting

confidence: 93%

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Phytochemical, antimicrobial and cytotoxic evaluation of Indigofera serpentinicola

Kahiya

Zimudzi

2015

Bangladesh J Pharmacol

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Section: Resultssupporting

confidence: 93%

“…Of the various Indigofera species, Indigofera tinctoria and I. suffruticosum are well known for producing the dye indigo (Leite et al, 2003). Some Indigofera species are used in anti-cancer therapy (Vieira et al, 2006) and others for toothache, ulcers and swellings or as analgesics and anti-inflammatory agents (Prabakaran et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical, antimicrobial and cytotoxic evaluation of Indigofera serpentinicola

Kahiya

Zimudzi

2015

Bangladesh J Pharmacol

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“…Natural products, including extracts from medicinal plants, have been used for biomedical purposes (1)(2)(3), including the treatment of several human diseases, such as dyslipidemia and atherosclerosis (4), hepatitis (5), inflammatory diseases (6), osteoporosis and rheumatoid arthritis (7,8), neoplastic diseases (9-11) and bacterial and virus infections (12,13). However, there is scant information regarding the potential use of such products for the treatment of the β-hemoglobinopaties, β-thalassemia and sickle-cell anemia (SCA).…”

Section: Introductionmentioning

confidence: 99%

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

Fibach

Prus

Bianchi³

et al. 2012

Int J Mol Med

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Abstract. Thalassemia and sickle-cell anemia (SCA) present a major public health problem in countries where the number of carriers and affected individuals is high. As a result of the abnormalities in hemoglobin production, cells of thalassemia and SCA patients exhibit oxidative stress, which ultimately is responsible for the chronic anemia observed. Therefore, identification of compounds exhibiting both antioxidant and hemoglobin-inducing activities is highly needed. Our results demonstrate resveratrol to be such a compound. This was shown both in the human K562 cell line, as well as in erythroid precursors derived from normal donors and β-thalassemia patients. Resveratrol was shown to exhibit antioxidant activity and to stimulate the expression of the γ-globin genes and the accumulation of fetal hemoglobin (HbF). To the best of our knowledge, this is the first report pointing to such a double effect of resveratrol. Since this natural product is already marketed as an antioxidant, future investigations should concentrate on demonstrating its potential to augment HbF production in experimental animal models (e.g., thalassemia and SCA mice) as well as in patients. We believe that the potential of clinical use of resveratrol as an antioxidant and HbF stimulator may offer a simple and inexpensive treatment to patients.

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“…Total methanolic extracts of plant contain a wide range of polar and moderately non-polar compounds including alkaloids, sterols, triterpenes, flavonoids, carbohydrates and coumarins and etc (26).Chloroform, ethyl acetate, and water were used to provide fractions of methanolic extract. These solvents have different polarity.…”

Section: The Efficiency Of Spergularia Marina (L) Grisebmentioning

confidence: 99%

Evaluation of antioxidant and antimicrobial activity of Spergularia marina (L.) Griseb extract

Miri¹,

Ghalehnoo²,

Shaharaki³

2016

J. Fundam and Appl Sci.

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Spergularia marina (L.) Griseb is a species from spergularia genus (Caryophyllaceae). This genus has some medicinal effects such as antidiabetic, antioxidant and diuretic effect. Research Article A. Miri et al J Fundam Appl Sci. 2016, 8(2S), 501-517 502In this work, firstly the total phenolic and flavonoid contents of Methanolic extract and Chloroform, Ethyl acetate and Water fractions from Spergularia marina (L.) Griseb were calculated, and then the antioxidant activites of all samples were determined using three methods, DPPH radical scavenging, Reducing power and Ferrous Chelating activity assay.In this assays VitC, VitE, BHA, EDTA, rutin and gallic acid were used as reference compounds.The In all antioxidant methods, Methanolic extract was showed the highest antioxidant activity and chloroform extract was the lowest antioxidant activity (aerial parts, seeds and all parts of plant). The results show methanolic extract of all parts of plant have any effect against above microorganisms.

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Antimicrobial Activity of Indigofera suffruticosa

Cited by 57 publications

References 26 publications

Phytochemical, antimicrobial and cytotoxic evaluation of <i>Indigofera serpentinicola</i>

Phytochemical, antimicrobial and cytotoxic evaluation of <i>Indigofera serpentinicola</i>

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

Evaluation of antioxidant and antimicrobial activity of <i>Spergularia marina</i> (L.) Griseb extract

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