Antimicrobial activity of flower extracts against wound pathogens and fungi

Abirami, S.; Jabesta, J.; Renitta, R. Emilin; Anand, Daniel Alex; Samrot, Antony V.

doi:10.1016/j.crgsc.2021.100076

Cited by 9 publications

(3 citation statements)

References 26 publications

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“…Similar diversity was observed in Nigerian Aloe plant (A. vera A type) with other species from Germany, UK, and USA that clustered into clade A while clade D is distinctly clustering with other Nigerian variant species of A. vera from Missouri, USA. To a greater extent, the diversity of these plants reveals genomic unrelatedness with high polymorphism despite the geographical origin [50]. This could infer other A. vera in these clades possess high-level antimicrobial properties as they shared related genetic makeup [51].…”

Section: Figure 4: Phylogenetic Diversity Of Nigerian Aloe Vera Variants With Repository a Vera Metadata Deposited In Genbank (Colored Blmentioning

confidence: 98%

“…Thus, showing the usefulness of genetic diversity as a reliable tool for improved taxonomy of A. vera of medicinal importance. Genetic diversity clearly predicts classification and identification of antimicrobial A. vera species sharing a typical genomic nucleotide profile [52], phylogenetic variation, and signature on nuclear DNA regions as reliable markers for characterization of homogeneity and detection of adulterant variants [50]. This would assure quality control in medicinal plant research and the production, clinical use, and forensic examination of A. vera to develop antimicrobial agents [51].…”

Section: Figure 4: Phylogenetic Diversity Of Nigerian Aloe Vera Variants With Repository a Vera Metadata Deposited In Genbank (Colored Blmentioning

confidence: 99%

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Antibacterial kinetics and phylogenetic analysis of Aloe vera plants

Akinduti

Obafemi

Isibor

et al. 2021

Open Access Maced J Med Sci

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Uncontrolled use of antibiotics has resulted in the emergence of resistant bacteria. It has necessitated the evaluation of antibacterial activities and phylo-diversity of Aloe vera (also called Aloe barbadensis) plants as antimicrobial agent in Nigeria. Biotyped enteric bacilli of 251 strains obtained from fecal samples of patients with various gastro-intestinal complications are profiled for antibiogram. Resistant biotypes were assayed for susceptibility to Aloe vera latex and further evaluated for time-kill kinetics and phylo-diversity. More than 30% of enteric bacilli, including Citrobacter freundii, Escherichia coli and Proteus mirabilis were resistant to cotrimoxazole, ciprofloxacin, and tetracycline respectively at MIC >16 µg/ml (p=0.004). Aloe vera latex significantly inhibited 39.5% resistant enteric biotypes with a significant average reduction of the viable count at 1xMIC and 2xMIC to less than 3.0 Log10CFU/mL after 24 hours. Flavonoids, alkaloids, terpenoids and anthraquinine in anti-enteric sap significantly correlated and regressed with antibacterial activity (p<0.05), while two of the antimicrobial Aloe vera plants showed phylogenetic relatedness with other homologous. Anti-bacteria efficacy of some Nigerian Aloe vera latex could provide alternative therapy, while its phylo-diversity and genomic profiling would offer a promising avenue for identification and development of antimicrobial agents as drug candidates for natural antibiotics.

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Section: Figure 4: Phylogenetic Diversity Of Nigerian Aloe Vera Variants With Repository a Vera Metadata Deposited In Genbank (Colored Blmentioning

confidence: 98%

Section: Figure 4: Phylogenetic Diversity Of Nigerian Aloe Vera Variants With Repository a Vera Metadata Deposited In Genbank (Colored Blmentioning

confidence: 99%

Antibacterial kinetics and phylogenetic analysis of Aloe vera plants

Akinduti

Obafemi

Isibor

et al. 2021

Open Access Maced J Med Sci

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“…Pharmacological pro le of the P. murex is also well explored and documented. Various parts of the plant exhibit antimicrobial activity (moderate activity), anti-in ammatory, anti-nephrolithic, anti-hyperlipidemia, antioxidant, antiulcer, anti-pyretic; aphrodisiac, hepatoprotective, nephroprotective, increases testosterone properties (Balamurugan et al, 2010;Srinivas et al, 2011;Siva et al 2012;Ananth 2018;Rathur 2019;Madhvan et al 2020;Ramadevi et al 2020;Abirami et al 2021)…”

Section: Propagation and Cultivationmentioning

confidence: 99%

Pedalium murex L.: Potential genetic resource for herbal medicine and mucilage

Shekhar

Rathur

Singh

et al. 2021

Preprint

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Pedalium murex (Pedaliaceae), commonly known as large caltrops in English and bada gokharu in Hindi is an underutilized mucilaginous medicinal herb having multiple uses in traditional system of medicine. It is mainly used to cure reproductive disorders, like impotency in men, nocturnal emissions, gonorrhoea as well as leucorrhoea in women. It is also useful in the treatment of urinary and gastrointestinal tract disorders. The present paper deals with botanical identity, vernacular names, ecology, environmental requirement and growth conditions, origin and geographical distribution, morphological/botanical description, propagation and cultivation, usages as a source of food, mucilage, medicine and biodiesel, important Ayurvedic formulations, phytochemical and pharmacological profile, future prospect.

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