Antimicrobial activity of ethanol extracts ofAgaricus brasiliensisagainst mutans streptococci

Evaluation of antibacterial activity of Australian basidiomycetous macrofungi using a high-throughput 96-well plate assay

“…was ineffective against these same bacterial species (Janes et al, 2007). Previous studies have indicated that Agaricus may be a lucrative genus to investigate with regards to antibiotic activity; water extract of A. bisporus show activity against Gram−ve bacteria and the ethanol extract of Agaricus brasiliensis Wasser, M. Didukh, Amazonas & Stamets has been shown to be effective against Gram+ve bacteria (Tambekar et al, 2006;Lund, 2009). The water extract of Agaricus sp.…”

“…The agar well diffusion and disc diffusion methods are commonly used for antimicrobial activity testing but these methods have some limitations. For example, some compounds may be more diffusible and can produce a greater zone of inhibition despite their lower activity in comparison with less diffusible compounds that might be more active but may produce smaller zone of inhibition (Janes et al, 2007;Lund et al, 2009). Therefore, in the present study, a high-throughput 96-well microplate bioassay procedure was used.…”

A Review on Antistaphylococcal Secondary Metabolites from Basidiomycetes

“…Naphthoquinone derivatives, which are bright colored pigments identified from Q. cyanescens, exhibited potential antibacterial activity against E. coli with a DIZ value of 2-3mm. Quambalarine A (26) and mompain (27) are mainly active against bacterial strains. The antimicrobial activity described for both these compounds could be related to their selectivity towards mitochondria which centers the cellular energetic metabolism.…”

Efeito da extração de compostos fenólicos sobre a atividade antioxidante e antibacteriana in vitro de cogumelo-do-sol

“…Trabalhos têm relatado que o AbM apresenta atividade antibacteriana, como, por exemplo, na avaliação in vitro contra agentes patogênicos orais para humanos, tais como Streptococcus mutans (Lund et al, 2009), além de atividade antioxidante (Soares et al, 2009), antidiabética (Kim et al, 2005), forte atividade imunoestimulante (Yuminamochi et al, 2007), bem como efeitos antitumorais e anticâncer (Yu et al, 2009), entre outros.…”

“…Além disso, podem ser usados em aplicações dermatológicas, como cosméticos e também como suplementos na indústria de alimentos (Heleno et al, 2010). Da mesma forma, extratos naturais com ação antimicrobiana apresentam-se como uma alternativa terapêutica, em razão de nas últimas décadas o uso irracional de antimicrobianos ter determinado o surgimento de cepas de micro-organismos multirresistentes, impulsionando a comunidade científica para a descoberta de novas opções desses agentes (Lund et al, 2009).…”