Antimicrobial activity of actinomycetes isolated from mangrove soil in Tuban, East Java, Indonesia

Fatimah, Fatimah; SUROIYAH, FATICHATUS; SOLIKHA, NIKMATUS; RAHAYUNINGTYAS, NAZIL DWI; SURTININGSIH, TINI; Nurhariyati, Tri; Ni’matuzahroh, Ni’matuzahroh; AFFANDI, MOCH.; Geraldi, Almando; THONTOWI, AHMAD

doi:10.13057/biodiv/d230622

Cited by 6 publications

(4 citation statements)

References 42 publications

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“…Macroscopic observations show the characteristics of dry colonies: mycelium, rounded colonies, raised elevation, and wrinkled, white to dark gray (Figure 1). The characteristics are similar to previously reported actinomycetes from Mangrove (Katili and Retnowati 2017;Fatimah et al 2022;Quintero et al 2022) belonging to the genus Streptomyces.…”

Section: Characteristics Of Streptomyces Koyangensis Strain Shp 9-3supporting

confidence: 89%

Exploring the potency of Streptomyces koyangensis strain SHP 9-3 isolated from the soil of Enggano Island (Indonesia) as an antibacterial source

et al. 2023

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Abstract. Pahira DSJ, Damayanti E, Lisdiyanti P, Mustofa, Hertiani T. 2023. Exploring the potency of Streptomyces koyangensis strain SHP 9-3 isolated from the soil of Enggano Island (Indonesia) as an antibacterial source. Biodiversitas 24: 1460-1466. Streptomyces is a Gram-positive bacterium with the potential a produce beneficial antimicrobials. This study aimed to determine the antimicrobial activity, morphological characteristics, cytotoxicity, and chemical profile of S. koyangensis SHP 9-3. This bacterium was isolated from Enggano Island, Indonesia, and the morphological characteristics were determined using a Scanning Electron Microscope (SEM). Cultivation was conducted in the International Streptomyces Project (ISP-2) media using baffled flasks and a shaker incubator. The secondary metabolites were conducted on the extract against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans by a twofold dilution method. Concurrently, cytotoxicity testing was done on Vero cells. The extract’s chemical profile was analyzed using LC-MS/MS. The results showed a prominent antibacterial activity as the extract inhibited the growth of S. aureus and C. albicans at 7.81 µg/mL. However, a growth inhibition against E. coli was observed at 250 µg/mL and P. aeruginosa at 31.25 µg/mL. The cytotoxic test showed the IC50 value on Vero cells was 5,015 µg/mL, indicating that the extract was nontoxic against Vero cells. The chemical profile of the extract by LC-MS/MS revealed the presence of five major components, i.e., cyclo (Pro-Val) (C10H16N2O2), kuraramine (C12H18N2O2), 1,4-diphenyl-1-pentanone (C17H18O), (3S,4S)-4-amino-3-hydroxy-6-methyl heptanoic acid (C21H42N2O7), and 2-ethyl-8-methyl-2,8-diazaspiro (4,5) decane-1,3-dione (C11H18N2O2).

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Section: Characteristics Of Streptomyces Koyangensis Strain Shp 9-3supporting

confidence: 89%

Exploring the potency of Streptomyces koyangensis strain SHP 9-3 isolated from the soil of Enggano Island (Indonesia) as an antibacterial source

et al. 2023

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“…Organic sediments swept into mangroves by tides are inhabited by bacteria that decompose the organic debris and are primary contributors to carbon cycling [114]. Diverse bacteria in these populations are involved in many other essential ecological functions such as nitrogen fixation [115], photosynthesis [116], phosphate solubilisation [117], enzyme production [118], sulfate reduction [119], antibiotic production [120], anoxygenesis [121], and methanogenesis [122] (Table 3). Among fungi, the dominant fungal phyla are Ascomycetes and Basidiomycetes, which have been reported to be primarily associated with the survival of mangrove plants in waterlogged and nutrient-restricted environments [123] (Table 3).…”

Section: Reservoir Of Microbial Communitiesmentioning

confidence: 99%

Mangrove Health: A Review of Functions, Threats, and Challenges Associated with Mangrove Management Practices

Akram,

Hussain,

Mazumdar

et al. 2023

Forests

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Mangroves stand out as one of the most diverse and biologically significant natural systems in the world. Playing critical roles in maintaining the health and productivity of coastal ecosystems, mangroves provide a range of services and functions, including habitat for local fauna and flora, food and other goods, carbon sequestration, and protection from natural disasters such as storm surges and coastal erosion. It is also evident that mangroves face several threats, which have already led to the gradual depletion of mangrove areas worldwide. Based on the analysis of current and related historical literature and data, this review summarises mangrove functions and the threats and challenges associated with mangrove management practices. Our findings suggest that coastal development, expanded aquaculture, deforestation, climate change, and other associated implications such as eutrophication, diseases, and pollution are the major factors posing threats to mangrove sustainability. We also highlight the various challenges, such as land use conflict, a lack of stringent regulatory actions, inadequate policy and government frameworks, and a lack of community awareness, that underlie ineffective mangrove management. The implementation of inclusive and coordinated approaches involving stakeholders from different backgrounds and interests, governmental and non-governmental organisations, and academia is essential for mangrove restoration and sustainable mangrove management by adapting mitigation strategies.

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“…Like geranylpyrrol A, the anandins A and B, prevalent among Streptomyces anandii extracts, comprise pyrrole rings and elucidate temperate antibacterial performance [168,169]. The glycosylated piericidins glucopiericidinol A3 and 7-demethyl-glucopiericidin A were found among Streptomyces sp.…”

Section: Streptomyces Sp Terpenoidsmentioning

confidence: 99%

New Insights on Biological Activities, Chemical Compositions, and Classifications of Marine Actinomycetes Antifouling Agents

Morgan,

Ali,

Alshahrani

et al. 2023

Microorganisms

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Biofouling is the assemblage of undesirable biological materials and macro-organisms (barnacles, mussels, etc.) on submerged surfaces, which has unfavorable impacts on the economy and maritime environments. Recently, research efforts have focused on isolating natural, eco-friendly antifouling agents to counteract the toxicities of synthetic antifouling agents. Marine actinomycetes produce a multitude of active metabolites, some of which acquire antifouling properties. These antifouling compounds have chemical structures that fall under the terpenoids, polyketides, furanones, and alkaloids chemical groups. These compounds demonstrate eminent antimicrobial vigor associated with antiquorum sensing and antibiofilm potentialities against both Gram-positive and -negative bacteria. They have also constrained larval settlements and the acetylcholinesterase enzyme, suggesting a strong anti-macrofouling activity. Despite their promising in vitro and in vivo biological activities, scaled-up production of natural antifouling agents retrieved from marine actinomycetes remains inapplicable and challenging. This might be attributed to their relatively low yield, the unreliability of in vitro tests, and the need for optimization before scaled-up manufacturing. This review will focus on some of the most recent marine actinomycete-derived antifouling agents, featuring their biological activities and chemical varieties after providing a quick overview of the disadvantages of fouling and commercially available synthetic antifouling agents. It will also offer different prospects of optimizations and analysis to scale up their industrial manufacturing for potential usage as antifouling coatings and antimicrobial and therapeutic agents.

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Antimicrobial activity of actinomycetes isolated from mangrove soil in Tuban, East Java, Indonesia

Cited by 6 publications

References 42 publications

Exploring the potency of Streptomyces koyangensis strain SHP 9-3 isolated from the soil of Enggano Island (Indonesia) as an antibacterial source

Exploring the potency of Streptomyces koyangensis strain SHP 9-3 isolated from the soil of Enggano Island (Indonesia) as an antibacterial source

Mangrove Health: A Review of Functions, Threats, and Challenges Associated with Mangrove Management Practices

New Insights on Biological Activities, Chemical Compositions, and Classifications of Marine Actinomycetes Antifouling Agents

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