Antimicrobial Activities in Some Argentine Medicinal Plants

Amani, Sara; Isla, Marı́a Inés; Vattuone, Marta Amelia; Poch, M.P.; Cudmani, N.G.; Sampietro, Antonio Rodolfo

doi:10.17660/actahortic.1999.501.15

Cited by 9 publications

(7 citation statements)

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“…and one of the main chemical components, nordihydroguayaretic acid (ANHG) [2][3][4][5][6]. However, few studies are devoted to the antioxidant properties of L. cuneifolia [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Phenolic Profile and Antioxidant Activity of Ethanolic Extract of Larrea cuneifolia Cav. Leaves

Lorenzo

Gómez

Sabatino

et al. 2020

The 1st International Electronic Conference on Food Science and Functional Foods

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The genus of the Zygophyllaceae family includes evergreen shrub species. Background highlights the antioxidant and anti-tumor activity of Larrea divaricate and nordihydroguayaretic acid (NDGA) due to their potential as a dietary supplement and food preservative, but little is known about Larrea cuneifolia. The aim of this work was to determine the antioxidant characteristics of ethanolic extracts of L. cuneifolia leaves collected in the central valley of Catamarca (Argentina). Total polyphenols content (TP) was determined by Folin-Ciocâlteu and the phenolic profile by HPLC-PDA-QTOF. The antioxidant activity was measured by in vitro (FRAP, TEAC and DPPH) and cellular (HepG2 and Caco2 cells) assays. The phenolic compounds identified were mainly derivatives of NDGA and flavonols derivatives of quercetin, kaempferol, isorhamnetin and gossypetin. TP content and antioxidant activity exceeded the values reported for L. divaricata. With regard to cytotoxicity, an increase in this parameter could be observed with the increase in the concentration of polyphenols in both cell types. Furthermore, in cells exposed to H2O2, a significant decrease in reactive oxygen species (ROS) concentration was observed for HepG2 cells. This effect can be used to study compounds with bioactivity on tumor cells. L. cuneifolia is a species rich in phenolic compounds, with antioxidant properties, and is a potential source of bioactive compounds for the production of functional foods.

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“…and one of the main chemical components, nordihydroguayaretic acid (ANHG) [2][3][4][5][6]. However, few studies are devoted to the antioxidant properties of L. cuneifolia [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Phenolic Profile and Antioxidant Activity of Ethanolic Extract of Larrea cuneifolia Cav. Leaves

Lorenzo

Gómez

Sabatino

et al. 2020

The 1st International Electronic Conference on Food Science and Functional Foods

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“…So, orderly screening them may result in the detection of novel real antimicrobial compounds (Costa et al, 2008). The screening of plant extracts and plant products for antimicrobial activity has shown that floras represent a potential source of new anti-infective agents (Amani et al, 1998;Costa et al, 2008). Many researches have carried out to screen natural products for antimicrobial property (Nair and Chanda, 2006).…”

Section: Introductionmentioning

confidence: 99%

In vitro antibacterial activity of Rumex nervosus and Clematis simensis plants against some bacterial human pathogens

Tedila¹,

Assefa²

2019

Afr. J. Microbiol. Res.

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Due to quick growth of resistance and high cost of new generation antibiotics, lots of efforts were made to discover new antimicrobial agents from various sources. So, current study was assessed antibacterial activity of ethanol, methanol, acetone, diethyl ether and hexane l e a v e extracts of Rumex nervosus and Clematis simensis by used paper disc diffusion and broth dilution procedures against six human pathogenic bacterial strains. The pathogenic bacteria were Shigella dysenteriae, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella Typhi and Klebsiella pneumoniae were susceptible to ethanol, methanol and acetone extracts of the leaves of R. nervosus followed by C. simensis, but hexane extract didn't displayed any activity. The extreme inhibition zone of 16.3±0.57 mm was detected against E. coli by ethanol extract of R. nervosus and MIC of 3.125 mg/ml against E. coli and S. dysenteriae by methanol extract. The methanol extract of C. simensis formed a marked inhibition of 13.1±0.37 mm against E. coli and ethanol extract of C. simensis displayed activity against S. dysenteriae 14.4±0.45 mm and MIC of 6.25 mg/ml against S. Typhi. Four dissimilar antibiotics like ciprofloxin, tetracyclin, kanamycin and chloramphenicol were used as standard for tested antibacterial activity against six different human pathogens. The activities were recognized the presence of some secondary metabolites existed in the tested floras which have related with antibacterial activities.

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“…This situation, the undesirable side effects of certain antibiotics and the emergence of previously uncommon infections (Marchese and Shito, 2001;Poole, 2001) have forced scientists into looking for new antimicrobial substances from various sources like medicinal plants. The screening of plant extracts and plant products for antimicrobial activity has shown that higher plants represent a potential source of new anti-infective agents (Amani et al, 1998;Salvat et al, 2001;Ordoñez et al, 2003;Arias et al, 2004).…”

Section: Introductionmentioning

confidence: 99%