Antimicrobial Action of New, Proprietary Lining Cements

McComb, Dorothy; Ericson, Dan

doi:10.1177/00220345870660050601

Cited by 75 publications

(36 citation statements)

References 12 publications

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“…Previous studies have suggested that pH may influence a material's solubility [Yoshida et al, 1998] and material pH may also help to determine the antibacterial effect. For example, GICs have an acid pH at set and have a pronounced effect on S. mutans up to 2 days after setting [McComb and Ericson, 1987]. The antibacterial activity of GICs has been attributed to the fluoride release and acidic pH [DeSchepper et al, 1989a, b].…”

Section: Bacterial Growthmentioning

confidence: 99%

Ion Release from Copper Phosphate Cement and Influence on <i>Streptococcus mutans</i> Growth in vitro: A Comparative Study

Foley

Blackwell

2003

Caries Res

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The aim of this study was to compare the effects of a black copper cement (BCC), an established restorative material (a conventional glass ionomer cement) and two temporary restorative materials (a zinc phosphate and a zinc polycarboxylate cement) on the growth of Streptococcus mutans in vitro, and to correlate bacterial growth with ion release from each material. Test specimens were eluted in either 0.1 M lactic acid, pH 4, or 0.1 M sodium chloride, pH 7. At 2 days, 7 days, 28 days and 6 months, eluates were inoculated with S. mutans and bacterial growth was recorded. Metal ion (Cu²⁺, Zn²⁺and Mg²⁺) and fluoride release were measured. At most immersion times, the different materials had a statistically significant inhibitory effect on bacterial growth compared to the respective control, at both pH levels. The inhibitory effect decreased with time and in most cases was associated with high levels of ion release at the beginning of the experimental period, followed by significantly lower levels. For BCC, there were statistically significant relationships between the median rates of growth of S. mutans in the presence of BCC eluates and the median values for release of copper and zinc, although not magnesium. Of the different materials, BCC demonstrated greatest antibacterial activity.

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Section: Bacterial Growthmentioning

confidence: 99%

Ion Release from Copper Phosphate Cement and Influence on <i>Streptococcus mutans</i> Growth in vitro: A Comparative Study

Foley

Blackwell

2003

Caries Res

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“…1990Forsten. , 1994, Studies have in dicated that glass ionomer cements and fluoride-releasing composite resins have the ability to inhibit secondary caries at the restoration margin [Donly and Gomez, 1994;GarciaGodoy and Jensen, 1990;Griffin et ah, 1992;Jensen et ah, 1991;Tysowsky et ah, 1988;Zimmerman et ah, 1984], Fur thermore, there appears to be an immediate reduction of bacteria adjacent to fluoride-releasing materials [Berg et ah, 1990;DeSchepper et ah, 1989;McComb and Ericson, 1987]. Not only would secondary caries be reduced at resto ration margins, but the adjacent interproximal tooth could also benefit from constant fluoride release.…”

mentioning

confidence: 99%

An in vitro Comparison of Three Fluoride Regimens on Enamel Remineralization

et al. 1997

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The purpose of this study was to compare the enamel remineralization effectiveness of a fluoride rinse, fluoridated dentifrice, and fluoride-releasing restorative material. Forty extracted molars had 1 × 5 mm artificial carious lesions formed at the interproximal contact point. One-hundred-micrometer sections were obtained at the caries sites, and polarized light photomicrographs were obtained. The sections had varnish placed, leaving only the external section site exposed, and were situated back into the original tooth. Forty other molars were obtained; 10 had Class-II glass ionomer cement restorations placed. These 40 teeth were mounted to have interproximal contact with the adjacent teeth containing artificial carious lesions. Specimens were placed in closed environments of artificial saliva for 1 month, with saliva being changed every 48 h. Ten specimen pairs were brushed with a fluoridated dentifrice for 2 min, twice per day, 10 specimen pairs were rinsed with a 0.05% sodium fluoride rinse for 1 min twice per day, 10 specimen pairs had Class-II glass ionomer cement restorations positioned adjacent to 10 teeth with artificial carious lesions, and 10 specimen pairs acted as controls. After 30 days, the same sections were photographed again under polarized light, and areas of the lesions were digitized quantitatively. Results demonstrated the mean ( ± SD) remineralization (μm²) in Thoulet’s 1.41 imbibition media to be: lesions adjacent to glass ionomer cement restorations, 2.45 ± 170; lesions exposed to a fluoridated dentifrice, 223 ± 102; lesions exposed to 0.05% sodium fluoride rinse, 374 ± 120, and control lesions only exposed to artificial saliva, 101 ± 69. Duncan’s analysis indicated the fluoridated rinse to have significantly greater remineralization effects on adjacent caries than the other groups (p ≤ 0.05). The glass ionomer restorative material and fluoridated dentifrice also had significantly greater remineralization effects on adjacent caries than the control, yet significantly less than the fluoridated rinse (p ≤ 0.05).

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“…Bacteriostatic properties possessed by the material itself are regarded as a further benefit of glass-ionomer cements [Tobias et al. 1985: McComb and Ericson. 1987: Scherer et al.…”

mentioning

confidence: 99%

The Effect of Glass-Ionomer Cement on Carious Dentine: An in vivo Study

Weerheijm

Soet²,

Amerongen³

et al. 1993

Caries Res

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The effect of a glass-ionomer cement sealant on carious dentine was investigated clinically and bacteriologically. The study group consisted of 24 molar teeth, with small clinical visible occlusal dentine lesions, in 13 children (aged 7–18 years). Twenty of these molars were filled and sealed with a glass-ionomer cement (Fuji Ionomer Type III®) and 4 with a resin sealant (Delton®). From each molar, two dentine samples were collected aseptically with a time interval of 7 months. The first sample was taken after opening the lesion just beneath the dentino-enamel junction before application of the filling material (sample A), and the second beneath the removed filling material (sample B) 7 months later. Before collecting sample B the sealant was clinically evaluated and impressions were prepared in order to (re)evaluate the sealants later by scanning electron microscopy (SEM). After taking the second sample, the remaining fissures were opened to a standard depth, the caries which was still present was removed, and a composite resin restoration was applied. In all teeth, more glass-ionomer cement material was found by SEM compared to the clinical evaluation. In both the glass-ionomer- and the resin sealant-treated group, the median value of the total number of microorganisms (CFU) on blood agar was 100 times smaller in the B sample. Microorganisms were found in 90% of the B samples in the group treated with glass-ionomer cement; hard dentine was also found in 45% of the B samples from this group. No significant differences were found between the groups in terms of dentine colour, hardness, or numbers and types of microorganisms (Fisher’s exact test, p > 0.05). There appears to be some evidence of an effect by glass-ionomer cement on the consistency of remaining carious dentine. However, it would be premature to conclude from the results obtained in this study that complete removal of carious dentine need not be carried out when using glass-ionomer cement.

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Antimicrobial Action of New, Proprietary Lining Cements

Cited by 75 publications

References 12 publications

Ion Release from Copper Phosphate Cement and Influence on <i>Streptococcus mutans</i> Growth in vitro: A Comparative Study

Ion Release from Copper Phosphate Cement and Influence on <i>Streptococcus mutans</i> Growth in vitro: A Comparative Study

An in vitro Comparison of Three Fluoride Regimens on Enamel Remineralization

The Effect of Glass-Ionomer Cement on Carious Dentine: An in vivo Study

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