Antilymphocyte Globulin Prepared by Precipitation with Rivanol in the Treatment of Acute Rejection Following Allogenic Renal Transplantation in the Dog

Abstract

Horse-antidog antilymphocyte immunoglobulin-G (ALIg-G) was prepared by precipitation with 2-ethoxy-6,9-diamino-acridine lactate (Rivanola). Twenty dogs received azathioprine in a small daily dose after allogenic renal transplantation. ALIg-G treatment was started as soon as a rejection crisis was suspected. Ten dogs receiving no other immunosuppressive therapy were given ALIg-G from the 4th day after allogenic renal transplantation. It appears that ALIg-G treatment may influence early acute rejection in the dog. Scand J Urol Nephrol6Scand J Urol Nephrol Downloaded from informahealthcare.com by Monash University on 02/04/15For personal use only.