Antiinflammatory Potential and Fatty Acid Content of Lipophilic Leaf Extracts of Four <i>Staphylea</i> L. Species

Laciková, Ľ; Pferschy‐Wenzig, Eva‐Maria; Maśterová, I; Grančai, D; Bauer, Rudolf

doi:10.1177/1934578x0900400420

Cited by 4 publications

(1 citation statement)

References 15 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Data from the literature on the chemical composition of the flowers and leaves have shown promising results, including notable cytotoxic and antibacterial properties [ 6 , 8 , 9 , 10 , 11 ]. Staphylea spp.…”

Section: Introductionmentioning

confidence: 99%

Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.

Paolillo,

Roscigno,

Innangi

et al. 2024

IJMS

View full text Add to dashboard Cite

Staphylea, also called bladdernuts, is a genus of plants belonging to the family Staphyleaceae, widespread in tropical or temperate climates of America, Europe, and the Far East. Staphylea spp. produce bioactive metabolites with antioxidant properties, including polyphenols which have not been completely investigated for their phytotherapeutic potential, even though they have a long history of use for food. Here, we report the isolation of six flavonol glycosides from the hydroalcoholic extract of aerial parts of Staphylea pinnata L., collected in Italy, using a solid-phase extraction technique. They were identified using spectroscopic, spectrometric, and optical methods as three quercetin and three isorhamnetin glycosides. Among the flavonol glycosides isolated, isoquercetin and quercetin malonyl glucoside showed powerful antioxidant, antimicrobial, and wound healing promoting activity and thus are valuable as antiaging ingredients for cosmeceutical applications and for therapeutic applications in skin wound repair.

show abstract

Section: Introductionmentioning

confidence: 99%

Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.

Paolillo,

Roscigno,

Innangi

et al. 2024

IJMS

View full text Add to dashboard Cite

show abstract

The Complete Chloroplast Genome Sequence of Staphylea holocarpa (Staphyleaceae)

Chen

Tong

et al. 2023

Mol Biotechnol

View full text Add to dashboard Cite

Isolation, identification and quantification of flavonoids from the flowers of <i>Staphylea pinnata</i> L.

Sokolova,

Poluyanov,

Bardakov

et al. 2024

Razrabotka i registraciâ lekarstvennyh sredstv

View full text Add to dashboard Cite

Introduction. Search for new plant species containing biologically active substances (hereinafter – BAS) is one of the leading tasks of pharmacognosy as a science. The search for flavonoid glycosides in plant raw materials is especially relevant, since they have anti-inflammatory, antioxidant, immunostimulating, as well as weak fungicidal and bacteriostatic action. Staphylea pinnata L. is an endemic plant of the Caucasus, cultivated not only in Georgia, but also in the Russian Federation in the Northern and Northwestern Caucasus. In foreign literature there are studies of antioxidant, antiproliferative and cytotoxic activity of leaf extracts of several species of S. pinnata L., as well as inhibitory activity of COX-1, COX-2 and LTB4 formation. Meanwhile, no serious Russian-language scientific studies on either the chemical composition or pharmacological action of generative organs of S. pinnata were found in the literature. This work is part of a comprehensive phytochemical study of S. pinnata. The aim of the work is to study the qualitative and quantitative composition of flavonoids in the studied object.Aim. To isolate, identify and quantify flavonoids in flowers and buds of Staphylea pinnata L.Materials and methods. Alcohol-water extracts from dried generative organs of the studied plant were used as analyzed solutions. Solutions were analyzed on a spectrophotometer SF-2000 (LLC "OKB Spectr", Russia) after sample preparation with aluminum chloride and on an HPLC Nexera-i LC-2040 (Shimadzu Corporation, Japan) equipped with a column and sample thermostat, degasser and autosampler using an individually selected elution gradient of the mobile phase (0.1 % orthophosphoric acid/acetonitrile solution). The primary data were processed using LabSolutions Single LC software (Shimadzu Corporation, Japan). Compounds from the flavonoid group were identified by retention times. Detection was carried out using a UV detector with an absorption wavelength of 365 ± 2 nm.Result and discussion. Alcohol-water extracts from flowers and buds of S. pinnata L. were obtained. Quantitative evaluation by spectrophotometry for flavonoid content was carried out. A gradient elution mode for HPLC was selected for simultaneous determination of 7 flavonoid glycosides. These chromatographic conditions allowed the identification and quantification of astragaline, cynaroside, cosmosiin, narcissin and rutin in flowers and buds of Staphylea pinnata L. Flavonoid glycosides: raponticin and kaempferol were not detected.Conclusion. Flavonoid glycosides were isolated from the generative organs of S. pinnata L., a technique for quantitative determination of flavonoid glycosides in alcohol-water extracts was developed, astragalin, cynaroside, cosmosiin, narcissin and rutin were detected and quantified.

show abstract

Antiinflammatory Potential and Fatty Acid Content of Lipophilic Leaf Extracts of Four Staphylea L. Species

Cited by 4 publications

References 15 publications

Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.

Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.

The Complete Chloroplast Genome Sequence of Staphylea holocarpa (Staphyleaceae)

Isolation, identification and quantification of flavonoids from the flowers of <i>Staphylea pinnata</i> L.

Contact Info

Product

Resources

About