Antiinflammatory Effect of Peripheral Nerve Blocks after Knee Surgery

Abstract

Nerve blocks inhibited clinical inflammation after total knee arthroplasty, with no change in tissue and plasma cytokine concentrations.

Cathéters sciatiques: une alternative analgésique chez les patients diabétiques

“…Seuls deux patients avaient une EN [ 18 Les douleurs chroniques sembleraient impacter le comportement quotidien des patients.…”

“…Fiftyfive perineural catheters were placed in 32 patients. The median duration of catheter placement across patients was 13 [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] days. No toxic or infectious complications were seen.…”

Persistent Postmastectomy Pain and Pain-Related Physical and Emotional Functioning With and Without a Continuous Paravertebral Nerve Block: A Prospective 1-Year Follow-Up Assessment of a Randomized, Triple-Masked, Placebo-Controlled Study

“…39,40 In contrast, persistent postoperative pain often results from nociceptive communication from injured peripheral tissue to the central nervous system via afferent nerves in the immediate postoperative period, and it is this communication that peripheral nerve blocks dramatically attenuate. 30 Interestingly, a recently published randomized trial by Karmakar et al 41 with a protocol very similar to that of the current study reported a similar decrease in the incidence and intensity of chronic pain 6 months after mastectomy, but only for subjects who received both a single-injection paravertebral block and subsequent 72-h perineural infusion compared with no regional anesthetic/analgesic.…”

Von der präemptiven zur präventiven Analgesie

“…der präventiven Analgesie [3,4] definiert. Einige klinische Studien, die umfassende multimodale schmerztherapeutische Verfahren einschließlich der Regionalanästhesie in der prä-, intra-und postoperativen Phase sowie deren Effekte auf Schmerzen, Funktionalität und Morbidität über die unmittelbar postoperative Phase hinaus untersuchen, weisen darauf hin, dass die präventive Analgesie, insbesondere durch Verfahren der Regionalanästhesie, tatsächlich vorteilhaft sein kann [5,6,7].…”