Antihypertensive effect of renal artery denervation performed with various generations of catheters

Abstract

The treatment of resistant hypertension remains difficult despite the progress made in the development of antihypertensive remedies. In this context, renal artery denervation has been shown to be effective and safe in clinical trials published over the past three years. The complex ablation of the main renal arteries and their small branches with a diameter over 4 mm obtained with second-generation catheters has demonstrated its superiority in reducing blood pressure compared to first-generation catheters, which allowed ablation to be performed only in the main branches of the renal arteries. The present paper presents part of the research conducted in the Department of Hypertension, its purpose being to evaluate the effectiveness of renal denervation in patients with resistant hypertension.