Antihypertensive drug therapy for mild to moderate hypertension during pregnancy

Ábalos, Edgardo; Duley, Lelia; Steyn, D.W.

doi:10.1002/14651858.cd002252.pub3

Cited by 309 publications

(289 citation statements)

References 116 publications

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“…The most commonly recommended agents are parenteral labetalol or hydralazine, 20,21 or sublingual nifedipine, oral immediate-acting nifedipine or oral intermediate-acting nifedipine. 20,22,23 We have learned from the United Kingdom's Con dential Enquiry into Maternal and Child Health that failure of effective antihypertensive therapy for severe hypertension is the most common source of sub-standard care of women with preeclampsia, even in well-resourced settings. 24 Relevant systematic reviews have failed to show clear differences between parenteral antihypertensive agents that would favour one over others.…”

Section: Geographica and Income Distribution Of Identi Ed Emls In 14mentioning

confidence: 99%

“…Although the most commonly recommended agents in pregnancy are oral methyldopa, labetalol, beta blockers, and calcium channel blockers, 25 relevant systematic reviews indicate neither clear bene ts of treatment nor clear differences between one agent or another. 22 What has been shown is that treatment of non-severe hypertension will decrease the incidence of BP values of ≥ 160/100 mmHg later in pregnancy. 22 Life-saving medications from EMLs have been condensed to form the Priority Medicines for Mothers and Children released by the WHO in 2011.…”

Section: Geographica and Income Distribution Of Identi Ed Emls In 14mentioning

confidence: 99%

“…22 What has been shown is that treatment of non-severe hypertension will decrease the incidence of BP values of ≥ 160/100 mmHg later in pregnancy. 22 Life-saving medications from EMLs have been condensed to form the Priority Medicines for Mothers and Children released by the WHO in 2011. 26 This document did not address the treatment of severe hypertension, although we have successfully advocated for the addition of an antihypertensive agent for the 2012 version.…”

Section: Geographica and Income Distribution Of Identi Ed Emls In 14mentioning

confidence: 99%

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Pharmacotherapy for Preeclampsia in Low and Middle Income Countries: An Analysis of Essential Medicines Lists

Lalani

Firoz

Magee

et al. 2013

Journal of Obstetrics and Gynaecology Canada

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Objective: To determine the prevalence of drugs for comprehensive management of preeclampsia in national essential medicine lists (EMLs) in low and middle income countries (LMICs) Methods:We collected EMLs from the 144 LMICs identi ed by the World Bank through broad-based Internet searches and in collaboration with the World Health Organization We identi ed therapies for hypertension, eclampsia, preeclampsia complications (eg, pulmonary edema, thrombosis), preterm birth, and labour induction contained in the EMLs Resuts:In 91 EMLs obtained from 144 LMICs, the most commonly listed parenteral antihypertensive therapies were verapamil (637%), hydralazine (615%), sodium nitroprusside (483%), and propranolol (396%) The most prevalent oral antihypertensive therapies were nifedipine (956%), methyldopa (934%), propranolol (901%), and atenolol (879%) For eclampsia/ preeclampsia, magnesium sulphate was present in 846% of EMLs and calcium gluconate in 857% For pulmonary edema, most EMLs (945%) listed oral furosemide, for thrombosis 923% listed heparin, for acceleration of fetal pulmonary maturity 901% listed parenteral dexamethasone, and for labour induction 978% listed oxytocin or a prostanoid (usually misoprostol, 407%) Concusion: EMLs of LMICs provide comprehensive coverage of preeclampsia pharmacotherapy These EMLs may be used as advocacy tools to ensure the availability of these therapies within each country RésuméObjectif : Déterminer la prévalence des médicaments permettant la prise en charge exhaustive de la prééclampsie au sein des listes de médicaments essentiels (LME) nationales des pays ne disposant que d'un revenu faible ou moyen (PRFM)Méthodes : Nous avons regroupé les LME des 144 PRFM identi és par la Banque mondiale par l'intermédiaire de recherches généralisées sur Internet et en collaboration avec l'Organisation mondiale de la santé Nous avons identi é, au sein des LME, les traitements visant l'hypertension, l'éclampsie, les complications de la prééclampsie (p ex oedème pulmonaire, thrombose), l'accouchement préterme et le déclenchement du travailRésutats : Au sein des 91 LME obtenues auprès de 144 PRFM, les traitements antihypertenseurs parentéraux apparaissant le plus couramment ont été les suivants : vérapamil (63,7 %), hydralazine (61,5 %), nitroprussiate de sodium (48,3 %) et propranolol (39,6 %) Les traitements antihypertenseurs oraux les plus prévalents ont été les suivants : nifédipine (95,6 %), méthyldopa 216 l MARCH JOGC MARS 2013 OBSTETRICS (93,4 %), propranolol (90,1 %) et aténolol (87,9 %) Pour ce qui est de l'éclampsie / la prééclampsie, le sulfate de magnésium gurait dans 84,6 % des LME et le gluconate de calcium, dans 85,7 % de celles-ci Pour ce qui est de l'oedème pulmonaire, le furosémide oral gurait dans la plupart des LME (94,5 %); pour ce qui est de la thrombose, l'héparine gurait dans 92,3 % des LME; pour ce qui est de l'accélération de la maturité pulmonaire foetale, la dexaméthasone parentérale gurait dans 90,1 % des LME; et pour ce qui es...

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Section: Geographica and Income Distribution Of Identi Ed Emls In 14mentioning

confidence: 99%

Section: Geographica and Income Distribution Of Identi Ed Emls In 14mentioning

confidence: 99%

Section: Geographica and Income Distribution Of Identi Ed Emls In 14mentioning

confidence: 99%

See 1 more Smart Citation

Pharmacotherapy for Preeclampsia in Low and Middle Income Countries: An Analysis of Essential Medicines Lists

Lalani

Firoz

Magee

et al. 2013

Journal of Obstetrics and Gynaecology Canada

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show abstract

“…Hypertensive disorders are the second most common cause of maternal deaths worldwide (2) . There are several major categories of hypertensive disorders in pregnancy ranging from mild to moderate rise in blood pressure without proteinuria (usually called pregnancy induced hypertension (PIH)), preeclampsia (hypertension with proteinuria), severe preeclampsia and eclampsia (3) . Maternal hypertension, even of the mild to (4) .…”

Section: Introduction:-mentioning

confidence: 99%

Serum Total Calcium, Magnesium, Sodium and Potassium in Sudanese Women With Preeclampsia.

Sidahmed¹,

Abubaker²,

Elfadil³

2017

IJAR

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“…Early onset of labor or premature rupture of membranes are among the conditions that lead to delivering preterm; however, background variables like preeclampsia and hypertensive complications are more common. The latter is easily detectable but antihypertensive treatment is mainly symptomatic to gain time and advance gestation before delivery [12]. Preterm delivery poses significant risk in diabetic pregnancy affecting fetal growth, too, and the causative pathways are poorly described.…”

mentioning

confidence: 99%

Consecutive measurements show association of IGF-1 with preterm delivery in type 1 diabetic pregnancy

Lauszus¹,

Tjessem²,

Svarrer³

et al. 2017

Integr Obesity Diabetes

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Antihypertensive drug therapy for mild to moderate hypertension during pregnancy

Cited by 309 publications

References 116 publications

Pharmacotherapy for Preeclampsia in Low and Middle Income Countries: An Analysis of Essential Medicines Lists

Pharmacotherapy for Preeclampsia in Low and Middle Income Countries: An Analysis of Essential Medicines Lists

Serum Total Calcium, Magnesium, Sodium and Potassium in Sudanese Women With Preeclampsia.

Consecutive measurements show association of IGF-1 with preterm delivery in type 1 diabetic pregnancy

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