Antihypertensive adherence and outcomes among community‐dwelling Medicare beneficiaries: the Atherosclerosis Risk in Communities Study

Federspiel, Jerome J.; Kucharska‐Newton, Anna; Beyhaghi, Hadi; Zhou, Lei; Virani, Salim S.; Rodgers, Jo E.; Chang, Patricia; Stearns, Sally C.

doi:10.1111/jep.12659

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…[3][4][5] Moreover, there remains an issue with adherence to antihypertensive medications despite their efficacy in controlling hypertension and reducing cardiovascular events. 7,8 Non-adherence is associated with many factors, including inadequate insurance, 9 age, race/ethnicity, and income. 8 Past studies have focused on the relationship between gender and the utilization and effectiveness of antihypertensive medications among the U.S. adults, yet gender-specific guidelines for the treatment of hypertension and blood pressure control goals remain unaddressed.…”

Section: Introductionmentioning

confidence: 99%

Use and outcomes of antihypertensive medication treatment in the US hypertensive population: A gender comparison

Ullah

Khan

Bazargan‐Hejazi

et al. 2023

Health Promot Perspect

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Background: Although effective antihypertensive medications have existed for decades, only about half of the hypertensive individuals are considered to have controlled blood pressure. Limited research studies have investigated gender disparity in the utilization and effectiveness of antihypertensive medications treatment. To examine the gender difference in antihypertensive medications’ use and the effect of using antihypertensive medication treatment on blood pressure control among the U.S. adult with hypertension. Methods: Analysis of National Health and Nutrition Examination Survey (NHANES) data from (1999-2012) including individuals≥18 years old with hypertension. Study variables included gender, age, race/ethnicity, obesity, smoking, comorbidities, treatment medication type, and continuity of care. We used multivariate logistic regression in STATA V14. The data is presented as adjusted odds ratios (ORs) and 95% confidence interval (CI). Results: Of the 15719 participants, 52% were female. 49% of the antihypertensive medication users had their blood pressure under control (95% CI). In the adjusted logistic regression analysis, use of antihypertensive medications was found to be 12% greater in females as compared to males (OR=1.12; CI=1.02-1.22; P<0.05). No association between gender and blood pressure control was found. Blood pressure control was less likely achieved among 50 years or younger individuals, Blacks and Hispanics, obese, and those taking calcium channel blocker (CCB). Conclusion: Hypertensive females are more likely than males to use antihypertensive medications. The effectiveness of treatment to control blood pressure is equal across males and females. Our findings have implications for practitioners to account gender-specific approaches when discussing adherence to hypertension medication treatment with their patients.

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Section: Introductionmentioning

confidence: 99%

Use and outcomes of antihypertensive medication treatment in the US hypertensive population: A gender comparison

Ullah

Khan

Bazargan‐Hejazi

et al. 2023

Health Promot Perspect

View full text Add to dashboard Cite

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Social Risk Factors for Medication Nonadherence: Findings from the CARDIA Study

et al. 2020

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Objectives: Nonadherence to medications has been documented, but the combined effect of social risk factors on medication nonadherence has not been investigated. Methods: We conducted a cross-sectional analysis of data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based prospective cohort. The sample (N = 1506) included subjects who at Year 20 (2005-06) were taking prescription medications and completed a 4-item Medication Adherence Scale. Social risk factors were education of high school or less, annual household income <$25,000, high financial strain, high chronic stress, low social support, and high social strain. Results: In a fully adjusted logistic regression model, income <$25,000 (OR = 2.37 [95% CI 1.12-4.98], p < .05) and high chronic stress (OR = 2.07 [95% CI 1.09-3.94], p < .05) were significantly associated with medication nonadherence. Individuals with ≥3 social risk factors had >3 times higher odds of nonadherence than counterparts with no social risk factors (OR = 3.26 [95% CI 1.72–6.19], p < .001). Conclusion: Low income and chronic stress are associated with medication nonadherence, and the odds of nonadherence increase with the accumulation of social risk factors. Findings may be used to develop risk prediction tools to identify individuals who can benefit from adherence-promoting interventions.

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Antihypertensive adherence and outcomes among community‐dwelling Medicare beneficiaries: the Atherosclerosis Risk in Communities Study

Cited by 2 publications

References 15 publications

Use and outcomes of antihypertensive medication treatment in the US hypertensive population: A gender comparison

Use and outcomes of antihypertensive medication treatment in the US hypertensive population: A gender comparison

Social Risk Factors for Medication Nonadherence: Findings from the CARDIA Study

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