Antihyperlipidemic and Antioxidant Activity of Syzygium Aromaticum Extract in Rats Fed Cycas Diet

Abstract

carcinogenesis of both rats and humans. 10,11 The study was aimed to assess the effect of S. aromaticum aqueous extract on lipid profile and some antioxidant parameters in the blood and liver of rats fed cycas containing diet. Materials and Methods CycasPlant and Spice (S. aromaticum) Cycas plant was acquired from Abraka Delta State. S. aromaticum (clove) was purchased from Ekpoma main market, Edo State. The cycas plant and clove were collected during March-April, 2018. The spice and cycas plant (Cycas revolute) were identified at Forest Research Institute of Nigeria, Ibadan, with voucher number of FHI 110603 and FHI 6013157596 deposited in their Herbarium. Experimental animalsEight weeks old albino Wistar rats with weight range of 100 -180 g was used for the study. The rats were purchased from the animal house in the Anatomy Department, Basic Medical School, Delta State University, Abraka. The animals were aclimatized for 7 days. They were housed in plastic cages with wire gauze. They had a 12h light/ dark cycle and fed with growers mash and had water ad libitum. Animals were maintained in accordance with the guidelines and protocol for care and standard use of laboratory animals by the Canadian Council and Faculty of Science ethical committee (with approved number, REC/FOS/20/010