Abstract:In oral glucose tolerance tests, methanol extract of boiled seeds of Cicer arietinum (MECA) significantly and dose-dependently reduced blood glucose levels in glucose-loaded mice by 27.7, 31.9, 36.2, and 42.2%, respectively, at doses of 50, 100, 200 and 400 mg per kg in comparison to a standard antihyperglycemic drug, glibenclamide, which reduced blood glucose levels by 48.2% at a dose of 10 mg per kg. In acetic acid induced writhing tests in mice, MECA at the afore-mentioned doses reduced the number of writhi… Show more
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