Antihyperglycemic Activities of Uli Banana Leaves on Oral Sugar Tolerance

Abstract

Banana has been widely cultivated. This study aimed to determine the antihyperglycemic activity of Uli banana leaves infusion. The antihyperglycemic activity was evaluated by oral glucose and sucrose tolerance test. A bolus of sugar was given after Uli banana leaves infusion and blood was sampled at 0, 15, 30, 60, 90 and 120 minutes for glucose analyses. The trapezoidal rule was used to determine the area under the curve (AUC) blood glucose. Infusion of Uli banana leaves 3.3 g/kg showed a significant decrease AUC (p<0.05) in the glucose tolerance test, while that of dose 0.8 g/kg reduced significantly (p<0.05) in the sucrose tolerance test. The results showed that Uli banana leaves infusion possesses antihyperglycemic effect in mice.

In Vitro and In Vivo Anti Hyperglycemic Evaluation of Sterculia quadrifida Bark through The Inhibition of Alpha Glucosidase

“…This condition indicates the mice were at the hyperglycemic level due to induction of sucrose. Increasing blood glucose levels in these mice were in accordance with several studies that indicated there was an increase blood glucose level in normal individuals after sugar administration orally (Gunawan-Puteri et al, 2020;Hendra et al, 2021). Other studies have reported an increase in glucose level of mice at 15 min after 4 g/kg sucrose administration (Poovitha et al, 2016;Gunawan-Puteri et al, 2018).…”