Antihistamine promotes electroacupuncture analgesia in healthy human subjects: A pilot study

Lee, Yu‐Chen; Tu, Cheng-Hao; Chung, Hsin-Yi; Luo, Sih-Ting; Chu, Yen-Chang; MacDonald, Iona; Kotha, Peddanna; Huang, Chien-Chen; Lane, Hsien Yuan; Lin, Jaung‐Geng; Chen, Yi-Hung

doi:10.1016/j.jtcme.2022.04.003

Cited by 1 publication

(1 citation statement)

References 39 publications

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“…In addition to the treatments described above, there are numerous over the counter medications, off brand medications, and alternative therapies that have shown promise in alleviating symptoms of fibromyalgia and its comorbidities. This brief list is not comprehensive, but treatments of note are the Transcutaneous Electrical Nerve Stimulation unit, antihistamines, and low dose naltrexone (67)(68)(69)(70). While there are theories as to the nature of FM, the underlying cause is still largely unknown, so treatment of the symptoms and comorbid conditions is key (71,72).…”

Section: Treatmentmentioning

confidence: 99%

Distress as a mediator for pain and activities of daily living in older adults with fibromyalgia

et al. 2022

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IntroductionPain, distress, and activities of daily living impact the lives of those with chronic pain. This study investigated distress (depressive symptoms, anxiety) on the relationship between pain (intensity and pain interference) and activities of daily living in individuals with fibromyalgia while controlling for age.MethodsThe current cross-sectional investigation focused on data from 123 men and women with fibromyalgia. Pain intensity, pain interference and anxiety were measured on 0-10 Likert type scales from the National Fibromyalgia Assessment Questionnaire. Depressive symptoms were assessed using the Beck Depression Inventory II. Activities of daily living (basic, instrumental) were measured with the Physical Activity Inventory Scale.ResultsIt was hypothesized that the relationships between pain intensity and pain interference and activities of daily living in individuals with fibromyalgia would be mediated by the construct of distress while controlling for age. Mediation significantly occurred in both models as predicted. However, those who were older reported lower levels of pain intensity and distress than their younger counterparts, which may be related to time since diagnosis or other factors.DiscussionResults of this study suggest that individuals with chronic pain conditions would benefit from treatment options which address distress, specifically depressive symptoms and anxiety.

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