BACKGROUNDHLA-B27 is associated with spondyloarthritis, a group of diseases that includes
psoriatic arthritis. OBJECTIVESTo describe the HLA-B27 frequency in a group of Brazilian patients with psoriatic
arthritis and correlate its presence or absence with their clinical
manifestations. METHODSCross-sectional study with 44 psoriatic arthritis patients of a Rheumatology
clinic. Demographic and social data were recorded, as were skin and joints
clinical examination. HLA-B27 was tested. All data were processed descriptively
and comparatively by appropriate software. Parametric and non parametric tests
were used with 5% statistical significance. RESULTSHLA-B27 was negative in 32 of the 44 patients (72,7%). Most of them were male,
Caucasian, living in Rio de Janeiro, with plaque type psoriasis and average age of
52,9 years. There was statistical significant correlation between positive HLA-B27
and male gender (p=0,004). Negative HLA-B27 had a tendency to correlate with hands
and wrists arthritis (p=0,07). There was an inverse significant correlation
between HLA values and Schöber's test (p=0,02). CONCLUSIONAlthough HLA-B27 is negative in most of patients, it is significantly associated
to male gender and inversely correlated with Schöber's test.