Antigenic and Genomic Variations Among Cytopathic and Non-Cytopathic Strains of Bovine Enteric Coronavirus

Experimental inoculation of adult dairy cows with bovine coronavirus and detection of coronavirus in feces by RT-PCR

“…Antigenic, biological and genomic variations among BCV strains have been reported [9,13]. Recently, we also detected some antigenic and biological diversity among BCV strains, but these variations were unrelated to the clinical source of the strains; i.e.…”

“…Bovine coronavirus causes neonatal CD and is also detected from adult cattle with WD. Based on epidemiological data, these disease syndromes often occur as separate and distinct outbreaks in herds; therefore differences in pathogenicity and antigenicity between CD and WD BCV might be expected [9,13,19]. However, isolates of WD BCV were reported to produce bloody diarrhea [17] or watery diarrhea [10] in newborn calves.…”

Pasture management effects on nonpoint source pollution of Midwestern watersheds

“…Bovine coronavirus (BCV) was first identified by Mebus et al (1972;1973a;1973b) and Stair et al (1972), and later this virus strain was diagnosed as a major cause of calf diarrhea. Coronaviruses, derived from the Latin word for crown, because of their shape, are pleomorphic, enveloped viruses with diameters ranging from 60 to 220 nanometers (Block and Schwartzbrod, 1989;Cavanagh and Macnaughton, 1995); but there have been documented variations in strains of bovine enteric coronaviruses (Dea et al, 1995). The genome of bovine coronavirus consist of RNA, responsible for sequencing and encoding matrix and nucleocapsid proteins with a molecular weight around 3.8 x 10 6 kDa (Saif and Heckert, 1990).…”