Antifungals susceptibility pattern of Candida spp. isolated from female genital tract our experience at a tertiary care teaching hospital

Abstract

Introduction: Vaginal candidiasis is considered as an essential general medical issue worldwide and its rate has expanded these days. As of late, unseemly and unbalanced utilization of antifungal medications, auto medication and in addition rebelliousness have caused tranquilize obstruction. Methods: This examination went for deciding the in vitro antifungal weakness examples of Candida species detached from female genital tract at IMS and SUM Hospital in Bhubaneswar, Odisha, India. Two hundred and fourthy five ladies (age run: 15 years to 49 years) going to the clinic were selected among January and December 2018 in this cross sectional investigation. Vaginal smears were gathered utilizing sterile swabs from every member and refined on sabouraud dextrose agar enhanced with chloramphenico l 0.5%; distinguishing proof of Candida spp. was performed following standard strategies. The plate dissemination technique was utilized for antifungal vulnerability testing. Results: Out of the 245 vaginal smears gathered, 94 (38.4%) strains of yeast were segregates among which 43 (45.7%) were Candida albicans and 51 (54.3%) were non albicans. The most elevated helplessness of the segregates was seen for nystatin 62 (83.78%), ketoconazole 61 (82.43%) and fluconazole 60 (81.08%). Conclusion: In spite of the detectable opposition of Candida spp. secludes to miconazole and itraconazole, the outcomes show that nystatin, ketoconazole and fluconazole are the medications of decision for the treatment of vaginal candidiasis in this area.