Antifungal susceptibility profile of Aspergillus fumigatus isolates from avian lungs

Spanamberg, Andréia; Ravazzolo, Ana Paula; Denardi, Laura Bedin; Hartz, Sydney A.; Santurio, Jânio M.; Driemeier, David; Ferreiro, Laerte

doi:10.1590/1678-5150-pvb-6297

Cited by 6 publications

(2 citation statements)

References 28 publications

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“…Only one of 159 independent isolates from Germany was found to be azole (itraconazole and voriconazole) resistant [ 39 ]. In the framework of epidemiological surveys, more extensive screening could increase the detectability of resistant Aspergillus fumigatus isolates and even a multi-resistance pattern, as demonstrated in poultry contexts [ 225 , 226 ].…”

Section: Treatmentmentioning

confidence: 99%

Aspergillosis in Wild Birds

Arné

Risco-Castillo

Jouvion

et al. 2021

JoF

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The ubiquitous fungi belonging to the genus Aspergillus are able to proliferate in a large number of environments on organic substrates. The spores of these opportunistic pathogens, when inhaled, can cause serious and often fatal infections in a wide variety of captive and free-roaming wild birds. The relative importance of innate immunity and the level of exposure in the development of the disease can vary considerably between avian species and epidemiological situations. Given the low efficacy of therapeutic treatments, it is essential that breeders or avian practitioners know the conditions that favor the emergence of Aspergillosis in order to put adequate preventive measures in place.

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Section: Treatmentmentioning

confidence: 99%

Aspergillosis in Wild Birds

Arné

Risco-Castillo

Jouvion

et al. 2021

JoF

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“…Regarding avian species, despite the importance of aspergillosis in these animals, there are few studies evaluating resistance or cryptic species. The majority of those reports are in poultry, and the rate of resistance is considered low thus far [ 70 , 82 , 108 , 109 ]. On the other hand, a few reports on Aspergillus susceptibility studies isolated from captive wild birds are described [ 110 , 111 ].…”

Section: Aspergillus Azole Resistancementioning

confidence: 99%

Aspergillosis, Avian Species and the One Health Perspective: The Possible Importance of Birds in Azole Resistance

et al. 2020

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The One Health context considers health based on three pillars: humans, animals, and environment. This approach is a strong ally in the surveillance of infectious diseases and in the development of prevention strategies. Aspergillus spp. are fungi that fit substantially in this context, in view of their ubiquity, as well as their importance as plant pathogens, and potentially fatal pathogens for, particularly, humans and avian species. In addition, the emergence of azole resistance, mainly in Aspergillus fumigatus sensu stricto, and the proven role of fungicides widely used on crops, reinforces the need for a multidisciplinary approach to this problem. Avian species are involved in short and long distance travel between different types of landscapes, such as agricultural fields, natural environments and urban environments. Thus, birds can play an important role in the dispersion of Aspergillus, and of special concern, azole-resistant strains. In addition, some bird species are particularly susceptible to aspergillosis. Therefore, avian aspergillosis could be considered as an environmental health indicator. In this review, aspergillosis in humans and birds will be discussed, with focus on the presence of Aspergillus in the environment. We will relate these issues with the emergence of azole resistance on Aspergillus. These topics will be therefore considered and reviewed from the “One Health” perspective.

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