Antifungal properties of Ocimum gratissimum essential oil (ethyl cinnamate chemotype)

Dubey, Nawal Kishore; Tiwari, Trayambak; Mandin, D.; Andriamboavonjy, Hary; Chaumont, Jean-Pierre

doi:10.1016/s0367-326x(00)00206-9

Cited by 81 publications

(14 citation statements)

References 3 publications

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“…Resveratrol has been shown to have anti-inflammatory and antioxidant activity and affects the initiation and progression of many diseases [28]. Ethyl cinnamate, a cinnamic acid ester, has already been approved as a flavor additive by the US Food and Drug Administration and has proven antifungal properties [29].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Phenolic and Flavonoid Compound Profiles and Antioxidant and α-Glucosidase Inhibition Properties of Cultivated Soybean (Glycine max) and Wild Soybean (Glycine soja)

Chen

Wang

Yuan

et al. 2021

Plants

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Wild soybean (Glycine soja Sieb.et Zucc; WS) has been used as a traditional food in China for many years and contains significantly higher levels of isoflavones than cultivated soybean (Glycine max; CS), but the secondary metabolites, including flavonoids and the phenolic composition differences between them, remain unclear. The results showed that WS possessed significantly higher total phenolic and flavonoid content and exhibited better antioxidant and α-glucosidase inhibition activities as well as excellent protective effects against H2O2-induced oxidative injury in a human endothelial cell line. Through metabolomic analysis, 642 metabolites were identified, and 238 showed differential expression, with 151 upregulated and 87 downregulated. A total of 79 flavonoid compounds were identified, 42 of which were upregulated in WS. 2′-Hydroxygenistein, garbanzol, protocatechuic aldehyde, ligustilide, and resveratrol were the most discriminated compounds in WS. The metabolic pathway analysis of differential metabolites related to the biosynthesis of flavonoids and phenolic acids were the biosynthesis of phenylpropanoids, flavonoids, isoflavonoids, flavones, and flavonols. This study substantially elucidated differences in the content of flavonoids and biological activities between WS and CS, which is useful information for the effective utilization of these two black soybean species in food processing.

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Section: Discussionmentioning

confidence: 99%

Comparison of Phenolic and Flavonoid Compound Profiles and Antioxidant and α-Glucosidase Inhibition Properties of Cultivated Soybean (Glycine max) and Wild Soybean (Glycine soja)

Chen

Wang

Yuan

et al. 2021

Plants

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“…Recent studies also demonstrate many therapeutic activities of the OG aqueous extract (OGE), including anti-inflammation 17, 20, analgesic and spasmolytic activities 21, antidiarrheal activity 13, antihyperglycemic activity 22, and improvement of phagocytic function 23. Notably, this extract has also shown potential properties to protect the user from hazardous bio-organisms, such as anthelminthic or insect-repellant properties, antibacterial, antifungal, and antiviral activity 24-28. Thus, some of more recent researches focus on its role of immune-modulation 29, 30, cancer chemoprevention 31, 34, and prevention of the vulnerability of immune disorder 30.…”

Section: Introductionmentioning

confidence: 99%

Ocimum gratissmum aqueous extract reduces plasma lipid in hypercholesterol-fed hamsters

et al. 2016

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Objectives: Hyperlipidemia is a significant risk factor in the development of atherosclerosis and related diseases which are major health problem in many developed and developing countries that can lead to fatality due to the changes in lifestyle and dietary habits in this modern age.Methods: In the present study, the Ocimum gratissimum aqueous extract (OGE) was tested for the lowering effect on the serum lipid level of male hamsters on a high-fat (12%) and high-cholesterol (0.2%) diet (HFCD).Results: The results showed that the levels of serum high-density-lipoprotein-cholesterol (HDL-C) low-density-lipoprotein-cholesterol (LDL-C), total cholesterol (TC), and triglycerols (TG) were increased in the HFCD group (113±11, 259±87, 629±175 and 625±262, respectively), as compared to the control normal diet group (51±8, 19±5, 77±16 and 101±44, respectively). When co-treated with various doses (10 and 20 mg/kg) of the OGE or rosuvastatin, the rats exhibited the restoration of normal serum LDL-C, TC, and TG levels.Conclusion: Therefore, we suggest that the Ocimum gratissimum aqueous extract may have the potential function of lowering serum lipid in rats.

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“…The antibacterial action of basil essential oil increases with the increase in levels of methyl chavicol (Pessoa et al 2002 Kishore Dubey et al 2000). The heterogeneity of oils may also be obtained by the synergistic effect of the different compounds (Ngassoum et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Effect of gibberellic acid (GA), indole acetic acid (IAA) and benzylaminopurine (BAP) on the synthesis of essential oils and the isomerization of methyl chavicol and trans-anethole in Ocimum gratissimum L

Hazzoumi,

Moustakime,

Amrani Joutei

2014

SpringerPlus

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Basil (O. gratissimum L) is a aromatic and medicinal plant widely used in traditional medicine in Morocco. The aim of this work was to study the effect of three plant growth regulators gibberellic acid (GA), indole 3-acetic acid (IAA) and benzylaminopurine (BAP) on the content and composition of essential oils of this plant, especially on the main compound (methyl chavicol) and its isomer (the trans-anethole).The results showed a wide variation on yield, content and range of the molecule constituent of oil, with a balance of appearances and/or disappearances of a few molecules.GA caused a slight decrease in the oil yield (0.2%), but it increased the diversity of compounds (17 molecules) with the appearance of four new compounds (naphthalene, camphor, germacrene-D, and ledene) and disappearance of (β cedrene, azulene). This variation also caused a very important decrease in the main compound (methyl chavicol) and increases its isomer (trans-anethole).IAA and BAP caused an increase in the yield of essential oil (0.30% and 0.32% respectively) without much influence on the main compounds, but with some change in the composition such as the appearance of (germacrene-D) and the disappearance of (aristolene).

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Antifungal properties of Ocimum gratissimum essential oil (ethyl cinnamate chemotype)

Cited by 81 publications

References 3 publications

Comparison of Phenolic and Flavonoid Compound Profiles and Antioxidant and α-Glucosidase Inhibition Properties of Cultivated Soybean (Glycine max) and Wild Soybean (Glycine soja)

Comparison of Phenolic and Flavonoid Compound Profiles and Antioxidant and α-Glucosidase Inhibition Properties of Cultivated Soybean (Glycine max) and Wild Soybean (Glycine soja)

Ocimum gratissmum aqueous extract reduces plasma lipid in hypercholesterol-fed hamsters

Effect of gibberellic acid (GA), indole acetic acid (IAA) and benzylaminopurine (BAP) on the synthesis of essential oils and the isomerization of methyl chavicol and trans-anethole in Ocimum gratissimum L

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