Antifungal prescribing pattern and attitude towards the treatment of oral candidiasis among dentists in Jordan

Al-Shayyab, Mohammad H.; Abu‐Hammad, Osama; AL‐Omiri, Mahmoud K.; Dar‐Odeh, Najla

doi:10.1111/idj.12173

Cited by 16 publications

(11 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first study was undertaken in the UK in 1987 and reported in 1989 [20]. The second study that conducted in the UK reported in 2004 [21].Furthermore, another study was undertaken in Jordan in 2015 [22].In accordance with those studies like the present study, nystatin was the most popular antifungal agent recommended (70.3%). In addition, nystatin oral suspension was selected by 73% of the respondents who suggested nystatin.…”

Section: Discussionsupporting

confidence: 83%

See 1 more Smart Citation

Current Antifungal Drug Prescribing to Treat Oral Thrush in Sulaimani City-Iraq

Rsaul

2018

UHD J SCI TECH

View full text Add to dashboard Cite

Oral thrush or oral candidosis is one of the most widespread fungal infections of the mucous membranes in human. This study aims to evaluate the pattern of prescribing of three antifungal drugs: nystatin, amphotericin B, fluconazole, and miconazole by the pharmacists and assistant pharmacists, which are used to treat oral thrush. A questionnaire was circulated to a random selection of pharmacies in Sulaimani city of Iraq between March 2017 and June 2017 and responses to were received from 101 pharmacies. The results were analyzed and the responses demonstrated as absolute and relative frequencies using Statistical Package for the Social Sciences Program (SPSS) version 21. Among the participants (65.3%) were males and (34.7%) were females. The participant's age range was (20 – 70) years. The majority (52.3%) holds a postgraduate degree as their highest educational level and they graduated after 2010. Miconazole and nystatin were the most popular choices of an antifungal agent that pharmacists would use, followed by fluconazole and amphotericin-B. The possibility of using miconazole was positively linked to recently graduated participants.

show abstract

Section: Discussionsupporting

confidence: 83%

“…In addition, miconazole and nystatin were also the commonly employed antifungals in studies that have been done by other researchers [19], [21], [22]. This is because these drugs may cause less intestinal irritation and other side effects.…”

Section: Discussionmentioning

confidence: 99%

Current Antifungal Drug Prescribing to Treat Oral Thrush in Sulaimani City-Iraq

Rsaul

2018

UHD J SCI TECH

View full text Add to dashboard Cite

show abstract

“… 11 , 18 One study showed that nystatin was the most commonly prescribed antifungal agent for the treatment of oral candidiasis in Jordan (78.2%). 38 …”

Section: Discussionmentioning

confidence: 99%

Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis

Lyu¹,

Zhao²,

Yan³

et al. 2016

DDDT

160

View full text Add to dashboard Cite

ObjectiveTo systematically review and assess the efficacy, different treatment protocols (formulation, dosage, and duration), and safety of nystatin for treating oral candidiasis.MethodsFour electronic databases were searched for trials published in English till July 1, 2015. Randomized controlled trials comparing nystatin with other antifungal therapies or a placebo were included. Clinical and/or mycological cure was the outcome evaluation. A meta-analysis or descriptive study on the efficacy, treatment protocols, and safety of nystatin was conducted.ResultsThe meta-analysis showed that nystatin pastille was significantly superior to placebo in treating denture stomatitis. Nystatin suspension was not superior to fluconazole in treating oral candidiasis in infants, children, or HIV/AIDS patients. The descriptive investigations showed that administration of nystatin suspension and pastilles in combination for 2 weeks might achieve a higher clinical and mycological cure rate, and using the nystatin pastilles alone might have a higher mycological cure rate, when compared with using nystatin suspensions alone. Nystatin pastilles at a dose of 400,000 IU resulted in a significantly higher mycological cure rate than that administrated at a dose of 200,000 IU. Furthermore, treatment with nystatin pastilles for 4 weeks seemed to have better clinical efficacy than treatment for 2 weeks. Descriptive safety assessment showed that poor taste and gastrointestinal adverse reaction are the most common adverse effects of nystatin.ConclusionNystatin pastille was significantly superior to placebo in treating denture stomatitis, while nystatin suspension was not superior to fluconazole in treating oral candidiasis in infants, children, or HIV/AIDS patients. Indirect evidence from a descriptive study demonstrated that administration of nystatin pastille alone or pastille and suspension in combination is more effective than that of suspension alone; prolonged treatment duration for up to 4 weeks can increase the efficacy of nystatin. More well designed and high quality randomized control studies are needed to confirm these findings.

show abstract

“…Diseases affecting teeth, their supporting structures and oral mucosa are best treated by operative interventions in the form of restorations, extractions, and periodontal therapy as well as other clinical interventions [2]. The need for therapeutic antimicrobial prescribing arises in a limited number of situations where operative intervention is either contraindicated or insufficient to achieve a complete resolution of inflammation [3,4].…”

Section: Introductionmentioning

confidence: 99%

Antibiotic Self-Medication for Oral Conditions: Characteristics and Associated Factors

Dar‐Odeh

Othman

Bahabri

et al. 2018

Pesqui. bras. odontopediatria clín. integr.

View full text Add to dashboard Cite

To investigate the prevalence and contributing factors of antibiotic selfmedication for oral conditions in dental patients. Material and Methods: A questionnaire was distributed to 501 patients attending Taibah University Dental College and Hospital, Al Madinah, Saudi Arabia during late 2016. Questions were on socio-demographic characteristics, and pattern of antibiotic self-medication for oral disease. Statistical analysis was performed using IBM SPSS software version 21. Statistical significance level was set at p ≤.05. Results: Age range was 15-64 years (29.08±9.32 years) with 297 females (59.3%) and 204 males (40.7%). 135 patients (27%) self-medicated with antibiotics for oral disease. This practice was statistically significantly associated with the older adults (p=0.001), lack of medical or dental insurance (p=0.014 and 0.007, respectively), and poor dental attendance (p=0.021). A number of 26 (25.7%) perceived analgesics as antibiotics. Amoxicillin-clavulanic acid was the most commonly cited antibiotic by 18 patients (17.8%). Dental pain was the most frequently reported oral condition. Pharmacists were the most common source for antibiotic prescription cited by 58 (57.4%). Conclusion: Antibiotic self-medication for oral disease is associated with the use of broad-spectrum antibiotics for non-indicated clinical oral conditions. The practice was encouraged by lenient behavior of pharmacists, lack of health insurance, and poor dental attendance.

show abstract

Antifungal prescribing pattern and attitude towards the treatment of oral candidiasis among dentists in Jordan

Abstract: The attitude towards the treatment of oral candidiasis is much better among the least-experienced dentists working in private practice. Nystatin and miconazole are the most popular choices of antifungal agents among Jordanian dentists.

Cited by 16 publications

References 55 publications

Current Antifungal Drug Prescribing to Treat Oral Thrush in Sulaimani City-Iraq

Current Antifungal Drug Prescribing to Treat Oral Thrush in Sulaimani City-Iraq

Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis

Antibiotic Self-Medication for Oral Conditions: Characteristics and Associated Factors

Contact Info

Product

Resources

About