Antifungal potentials of Luffa cylindrica (Roem) ethyl acetate leaf extract

Aboh, Mercy; Fidelis, Solomon; Oladosu, O. P.; Adeshina, G.; Olayinka, Busayo Olalekan; Olonitola, Steven

doi:10.31254/phyto.2020.9305

Cited by 4 publications

(1 citation statement)

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“…After drying, the leaves were grounded using porcelain mortar and pestle to reduce the sizes of the leaves, thereby increasing the surface area in contact with solvents to be used. Cold maceration method as reported by Aboh et al, [17] was used. About 200 g of the dried leaves were weighed and dispensed into 500 mL conical flask.…”

Section: Preparation Of Plant Extractmentioning

confidence: 99%

Antifungal Potential of Some Nigerian Indigenous Plants: A Remedy for Candidiasis

Aboh

Yakubu

Eze

et al. 2021

JAMB

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Background: Invasive candidiasis has been recognized as a major cause of mortality and morbidity in hospital settings across the globe. Aside from C. albicans, other Candida species (C. glabarata, C. parapsilosis, and C. tropicalis) associated with invasive candidiasis have been reported as a public health challenge. Objective: This study aimed to evaluate the antifungal activities of extracts of some indigenous plants using the agar disc diffusion method. Methods: Fresh samples of the plant parts were collected, identified, air dried, pulverized and extracted using standard methods. The extracts were screened against clinical isolates of C. albicans, C. glabarata, C. parapsilosis and C. tropicalis using agar disc diffusion method. Results: All plant extracts exhibited varying inhibition zones ranging from 8.0 - 24.0 mm against the tested isolates. Fractions of Acalypha wilkesiana Macrophylla (AWRF5) showed the lowest activities against all the test isolates with zones of inhibition ranging from 10.0-13.0 mm while AWRF6 fraction of the same plant demonstrated highest antifungal activities against all the test isolates with zones of inhibition ranging from 14.0-24 mm followed by fractions of Acalypha wilkesiana Hoffmanii (AWGF6), which demonstrated high (14.0 - 20.0 mm) antifungal activities. Conclusion: The Plants understudied possessed antifungal potentials and can serve as lead in the development of phytomedicines to combat candidiasis decrease medical as well as financial burden, hence improving the management of cirrhotic patients. These predictors, however, need further work to validate reliability.

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Section: Preparation Of Plant Extractmentioning

confidence: 99%

Antifungal Potential of Some Nigerian Indigenous Plants: A Remedy for Candidiasis

Aboh

Yakubu

Eze

et al. 2021

JAMB

View full text Add to dashboard Cite

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Review of herbal medicine works in the avian species

et al. 2021

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Poultry meat consumption is increasing worldwide but the overuse of antimicrobials for prevention and treatment of diseases has increased antimicrobial resistance (AMR), triggering a major public health issue. To restrict AMR emergence, the government supports the optimization of natural products that are safe and easy to obtain with minimal side effects on poultry, humans, and the environment. Various studies have explored the potential of herbs in animal health for their antiviral, antibacterial, antifungal, antiparasitic, immunomodulatory, antioxidant, and body weight gain properties. Therefore, this study reviewed plants with potential application in avian species by summarizing and discussing the mechanisms and prophylactic/therapeutic potential of these compounds and their plant origin extracts.

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Phytochemicals as potential active principal components for formulation of alternative antifungal remedies against Trichophyton spp.: a systematic review

Zhou,

Dzomba,

Gwatidzo

2024

Pure and Applied Chemistry

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In this age of emergent resistance to antimicrobial agents, pathogenic fungi are not an exception. Diverse strategies have been implemented to curb rampant fungal infections including screening new drugs and stewardship programs. A plethora of recent studies have proved that phytochemicals are efficacious against pathogenic fungi and have potent antifungal activity. This review examines the use of phytochemicals as possible alternative antifungal agents against dermatophytes particularly Trichophyton spp. Literature search was done using three search engines namely Google Scholar, PubMed and Science Direct limited to the year 2019–2023 only. A total of 30 articles were included and 48 plant extracts were evaluated. The major phytochemicals that proved to be potent antifungals both in vitro and in vivo were terpenoids and phenolics. The antifungal potential of phyto-compounds was significantly elevated by incarnation with nanotechnology. Although much has been done in screening of herbal extracts as possible antifungal agents huge gaps still exist on full characterization of all active herbal extracts with antifungal potential especially against resistant strains, together with their mechanism of action, formulation of pharmaceutical dosage forms and clinical trials.

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Antifungal potentials of Luffa cylindrica (Roem) ethyl acetate leaf extract

Cited by 4 publications

References 0 publications

Antifungal Potential of Some Nigerian Indigenous Plants: A Remedy for Candidiasis

Antifungal Potential of Some Nigerian Indigenous Plants: A Remedy for Candidiasis

Review of herbal medicine works in the avian species

Phytochemicals as potential active principal components for formulation of alternative antifungal remedies against Trichophyton spp.: a systematic review

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