Antifungal Effect of Three Local Malaysian Honeys on Selected Pathogenic Fungi of Otomycosis: An in vitro Evaluation

Hamid, Zubaidah Aimi Abdul; Mohamad, Irfan; Harun, Azian; Salim, Rosdan; Sulaiman, Siti Amrah

doi:10.5530/jyp.2018.10.91

Cited by 7 publications

(6 citation statements)

References 16 publications

(23 reference statements)

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“…In contrast to other local honey species, KH has been reported to possess stronger antioxidant activity and higher phenolic content [19,20]. It also has the potential to be used in the treatment of various medical conditions due to its anti-bacterial, anti-fungal and anti-cancer properties [21][22][23]. However, the effects of KH on MetS are still unknown.…”

Section: Introductionmentioning

confidence: 99%

The Beneficial Effects of Stingless Bee Honey from Heterotrigona itama against Metabolic Changes in Rats Fed with High-Carbohydrate and High-Fat Diet

Ramli

Chin

Zarkasi

et al. 2019

IJERPH

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Metabolic syndrome (MetS) is a group of conditions including central obesity, hyperglycemia, dyslipidemia, and hypertension that increases the risk for cardiometabolic diseases. Kelulut honey (KH) produced by stingless honey bees has stronger antioxidant properties compared to other honey types and may be a functional food against MetS. This study aimed to determine the efficacy of KH in preventing metabolic changes in rats with MetS induced by high-carbohydrate and high-fat (HCHF) diet. Male Wistar rats were randomly assigned to the control (C), HCHF diet-induced MetS (S), and MetS supplemented with KH (K) groups. The K group was given KH (1 g/kg/day) for eight weeks. Compared to the control, the S group had significant higher omental fat mass, serum triglyceride, systolic blood pressure, diastolic blood pressures, adipocyte area, and adipocyte perimeter (p < 0.05). KH supplementation significantly prevented these MetS-induced changes at week 16 (p < 0.05). Several compounds, including 4-hydroxyphenyl acetic acid, coumaric and caffeic acids, had been detected via liquid chromatography-mass spectrometry analysis that might contribute to the reversal of these changes. The beneficial effects of KH against MetS-induced rats provide the basis for future KH research to investigate its potential use in humans and its molecular mechanisms in alleviating the disease.

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Section: Introductionmentioning

confidence: 99%

The Beneficial Effects of Stingless Bee Honey from Heterotrigona itama against Metabolic Changes in Rats Fed with High-Carbohydrate and High-Fat Diet

Ramli

Chin

Zarkasi

et al. 2019

IJERPH

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“…When compared to other Malaysian honeys such as gelam and tualang, stingless bee honey has been found to be the most consistent in preventing bacterial development [15]. Furthermore, stingless bee honey was discovered to be the most effective in preventing fungal colony growth [16].…”

Section: Discussionmentioning

confidence: 99%

Perceptions on The Therapeutic Effects of Stingless Bee Honey and its Potential Value in Generating Economy among B40 Community of Kampung Bukit Kuin, Kuantan

Jalil

Damit

Zakaria

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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Meliponiculture or keeping stingless bee in Malaysia is expanding and has the potential to generate money for the the bottom 40% of income earners (B40). The increased production of stingless bee honey as a complementary medicine as a therapeutic medium for health for a variety of reasons. Thus, this study aimed to explore the experiences and perceptions on the therapeutic effects of stingless bee honey and its potential value in generating economy among the B40 community. Semi-structured interviews were carried out among the B40 community who participated in the Desa Kelulut project of Kampung Bukit Kuin, Kuantan. The data were analysed using thematic analysis. A total of six respondents interviewed in the study out of 20 participants. Four themes emerged, namely, benefit of stingless bee honey; market supply and economy; sustaining the farm; and facilitate income. The participants valued the beneficial properties of the honey toward health and acknowledged the potential of the stingless bee honey to be marketed in Malaysia as well as generating income for the B40 community of Kampung Bukit Kuin, Kuantan.

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“…This can lead us to the conclusion that there are other compounds that act may as enhancing factors for the observed antifungal activity. This notwithstanding, it was demonstrated that the inhibition degree on several pathogenic microorganisms depends on various honey concentrations, as observed in Tualang, Acacia and Kelulut honey against C. albicans and Aspergillus niger (5-25% v/v) [181]. In general, the outcomes suggest that the antifungal effects are intensified with an increased honey concentration [176,182].…”

Section: Antifungal Effectsmentioning

confidence: 92%

Towards a Better Understanding of Nutritional and Therapeutic Effects of Honey and Their Applications in Apitherapy

et al. 2021

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The nutritional and therapeutic aspects of natural products have gained more interest in recent years, owing to the importance that has been given to health and well-being. In this regard, honey represents an organic product whose high level of biologically active compounds and valuable nutrients have been extensively studied in order to prove its ability to provide an enhancement in health status. The use of honey in the process of healing or preventing certain diseases has been practiced throughout history and is now known as apitherapy. The aim of this review is to expand the knowledge and understanding towards the physicochemical characteristics of honey and the action of its main bioactive compounds towards health-beneficial properties (antioxidant, antimicrobial, antifungal, antiviral, etc.) for apitherapeutic purposes. Notwithstanding all the assets, the usage of honey for medical purposes encounters some limi-tations regarding the factors that may affect the therapeutic potential of honey in apitherapy that will be pointed out in this overview.

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Antifungal Effect of Three Local Malaysian Honeys on Selected Pathogenic Fungi of Otomycosis: An in vitro Evaluation

Cited by 7 publications

References 16 publications

The Beneficial Effects of Stingless Bee Honey from Heterotrigona itama against Metabolic Changes in Rats Fed with High-Carbohydrate and High-Fat Diet

The Beneficial Effects of Stingless Bee Honey from Heterotrigona itama against Metabolic Changes in Rats Fed with High-Carbohydrate and High-Fat Diet

Perceptions on The Therapeutic Effects of Stingless Bee Honey and its Potential Value in Generating Economy among B40 Community of Kampung Bukit Kuin, Kuantan

Towards a Better Understanding of Nutritional and Therapeutic Effects of Honey and Their Applications in Apitherapy

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