Antifungal effect and possible mode of activity of a compound from the marine sponge Dysidea herbacea

Sionov, Edward; Roth, Dalit; Sandovsky-Losica, H.; Kashman, Yoel; Rudi, Amira; Chill, Liat; Berdicevsky, Israela; Segal, Esther

doi:10.1016/j.jinf.2004.07.014

Cited by 41 publications

(33 citation statements)

References 11 publications

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“…[5][6][7][8] and marine algae [10]. The present study also supported the suggestion that in most species the major component has the diphenyl ether structure oxygenated at the 2,6′-position.…”

Section: Discussionsupporting

confidence: 89%

“…The simultaneous determination of OH-, OH-MeO-, and diOH-PBDEs in phenolic fractions are of great importance in monitoring studies of animals and humans, because these analogs exhibit a variety of bioactivities, depending on the structure (the presence of one or two hydroxyl groups in PBDE molecules) [7][8][9]. For example, diOH-PBDEs and OH-MeO-PBDEs are active against the Gram-positive bacterium Bacillus subtilis, whereas in their methylated analogs (diMeO-PBDEs), such activity is reduced [7].…”

Section: Discussionmentioning

confidence: 99%

“…The family Dysideidae, in particular, yields a number of hydroxylated polybrominated diphenyl ethers (OH-PBDEs), including dihydroxy (diOH), hydroxy-methoxy (OH-MeO), and dimethoxy (diMeO) analogs of tri-to hexa-BDEs [6,7]. These phenolic PBDE analogs exhibit a variety of bioactivities, such as antibacterial and antifungal properties [8], cytotoxicity, and enzyme inhibition [9]. Structure-activity relationships indicate that these activities may depend on the numbers and positions of hydroxyl groups [7].…”

Section: Introductionmentioning

confidence: 99%

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Selective determination of mono- and dihydroxylated analogs of polybrominated diphenyl ethers in marine sponges by liquid-chromatography tandem mass spectrometry

et al. 2012

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Selective determination of mono- and dihydroxylated analogs of polybrominated diphenyl ethers in marine sponges by liquid-chromatography tandem mass spectrometry

et al. 2012

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“…Cyanobacteria have been shown to produce brominated compounds such as bromodiphenyl ethers through an unknown mechanism, with the best-studied case being a filamentous cyanobacterial symbiont of a sponge (23). These brominated compounds have been found recently to cause leakage of fungal cell membranes (24), but the role of brominated compounds, if any, in CC9311 is open to speculation.…”

Section: Resultsmentioning

confidence: 99%

Genome sequence of Synechococcus CC9311: Insights into adaptation to a coastal environment

Palenik

Ren²,

Dupont

et al. 2006

Proc. Natl. Acad. Sci. U.S.A.

230

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Coastal aquatic environments are typically more highly productive and dynamic than open ocean ones. Despite these differences, cyanobacteria from the genus Synechococcus are important primary producers in both types of ecosystems. We have found that the genome of a coastal cyanobacterium, Synechococcus sp. strain CC9311, has significant differences from an open ocean strain, Synechococcus sp. strain WH8102, and these are consistent with the differences between their respective environments. CC9311 has a greater capacity to sense and respond to changes in its (coastal) environment. It has a much larger capacity to transport, store, use, or export metals, especially iron and copper. In contrast, phosphate acquisition seems less important, consistent with the higher concentration of phosphate in coastal environments. CC9311 is predicted to have differences in its outer membrane lipopolysaccharide, and this may be characteristic of the speciation of some cyanobacterial groups. In addition, the types of potentially horizontally transferred genes are markedly different between the coastal and open ocean genomes and suggest a more prominent role for phages in horizontal gene transfer in oligotrophic environments.cyanobacteria ͉ genomics ͉ marine

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“…In addition, wet mounts of tissue homogenates were stained with Calcofluor (Remel, Lenexa, KS) and were examined by fluorescence microscopy [17].…”

Section: Microscopy and Histopathology Of Infected Organsmentioning

confidence: 99%

Activity of an Intralipid formulation of nystatin in murine systemic candidiasis

Semis

Mendlovic

Polacheck

et al. 2011

International Journal of Antimicrobial Agents

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Antifungal effect and possible mode of activity of a compound from the marine sponge Dysidea herbacea

Cited by 41 publications

References 11 publications

Selective determination of mono- and dihydroxylated analogs of polybrominated diphenyl ethers in marine sponges by liquid-chromatography tandem mass spectrometry

Selective determination of mono- and dihydroxylated analogs of polybrominated diphenyl ethers in marine sponges by liquid-chromatography tandem mass spectrometry

Genome sequence of Synechococcus CC9311: Insights into adaptation to a coastal environment

Activity of an Intralipid formulation of nystatin in murine systemic candidiasis

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