Antifungal Constituents of the Essential Oil Fraction of Artemisia dracunculus L. Var. dracunculus

Abstract

The isolation and structure elucidation of antifungal constituents of the steam-distilled essential oil fraction of Artemisia dracunculus are described. Antifungal activities of 5-phenyl-1,3-pentadiyne and capillarin against Colletrotichum fragariae, Colletrotichum gloeosporioides, and Colletrotichum acutatum are reported for the first time. The relative abundance of 5-phenyl-1,3-pentadiyne is about 11% of the steam-distilled oil, as determined by GC-MS. Methyleugenol was also isolated and identified as an antifungal constituent of the oil.

Effects of Mace and Nutmeg on Human Cytochrome P450 3A4 and 2C9 Activity

“…dro-7-(5-methoxy-3,4-methylenedioxyphenyl)-3Ј-methoxy-8-methyl-1Ј-trans-propenylbenzofuran (8), 19) 1-acetoxy-2-(4-a l ly l -2 , 6 -d i m e t h ox y p h e n ox y ) -1 -( 3 , 4 -d i m e t h ox yphenyl)propane (9), 20) 7,8-dihydro-7-(3,4-methylenedioxyphenyl)-3Ј-methoxy-8-methyl-1Ј-trans-propenylbenzofuran (10), 15) myristicin (11), 15) methyleugenol (12), 21) 2,3-dimethoxy-5-(1-propenyl)-phenol (13), 22) safrole (14), 23) methoxyeugenol (15), 24) elemicin (16), 25) and eugenol (17) 26) ( Fig. 2).…”

Synthesis, Anti-Phytopathogenic and DPPH Radical Scavenging Activities of C-Prenylated Acetophenones and Benzaldehydes

“…Fungicidal activity assays of these compounds were performed in microcultures by growing the fungi in sterile Petri dishes (35 mm) at a final volume of 2 mL medium containing different compound concentrations. Clarified V8 (Campbell Soup) medium containing metalaxyl 46 for P. cinnamomi or PDA medium for B. cinerea and G. fujikuroi with captan 47,48 was used as the positive control [C(+)], and without fungicide as the negative control [C(−)]). The medium in each slot was then inoculated with a small block (4 mm) of clarified V8 or PDA medium containing fungal hyphae excised from the edge of an actively growing culture.…”

In Vitro and In Vivo Activity of Selected Plant Extracts against Papaya Carica papaya L.) Anthracnose (Colletotrichum gloeosporioides)

“…The findings of this study are in agreement with previous reports on the antifungal activity of Echinops sp., Ruta chalepensis, Thymus serrulatus and Artemisia genus [13,14,16,23]. Previous phytochemical investigation of Ruta chalepensis resulted in isolation of a number of alkaloids and coumarins and the active ingredients of this plant have antifungal properties that could prove beneficial to agriculture [12,24].…”

“…There is a need for continued research efforts to developing effective and economical alternative methods for the management of papaya anthracnose. Most plant specious used in this experiment had medicinal value and are known to contain a number of secondary substances with antimicrobial properties and are toxic to phytopathogens [6,[12][13][14][15][16][17].…”