Antifungal and cytotoxic activities of some N-substituted aniline derivatives bearing a hetaryl fragment

Practical One-Pot Synthesis of Secondary Amines by Zinc-Catalyzed Reductive Amination

“…The crude product was purified by column chromatography. The obtained analytical data are in agreement with literature reports [26,54,[69][70][71][72][73][74][75][76][77][78][79][80]. …”

Synthesis and antiproliferative activity of novel symmetrical alkylthio- and alkylseleno-imidocarbamates

“…Among the many moieties identified, the following are included in our series of chemical structures: furyl [33,34], thienyl [35,36], isoxazole [37,38], benzothiophene [39], benzodioxole [40], quinoline [41,42], phenylquinoline [43,44] and acridine [45,46].…”

Synthesis of new 4-methyl-2-(4-pyridyl)-1,2,3,4-tetrahydroquinolines as potent antifungal compounds

“…Both type of compounds displayed significant activity (MIC < 50 mg mL -1 ) against some pathogenic dermatophytes. [3][4][5][6] We found also that some 4-methyl-1,2,3,4-tetrahydroquinolines are active against yeasts, hialohyphomycetes as well as dermatophytes. A point of connection between homoallylamines and tetrahydroquinolines, apart from their similar type of bioactivity, is that the first ones are suitable precursors for the corresponding 2,4-substituted 1,2,3,4-tetrahydroquinolines via acid-promoted intramolecular 6-exo-trig cyclization, that was described in 1994 by our team.…”