Antifungal activity of Mongolian medicinal plant extracts

Giordani, Cristiano; Simonetti, Giovanna; Natsagdorj, Damdinsuren; Gotov, Choijamts; Ghirga, Francesca; Calcaterra, Andrea; Quaglio, Deborah; Angelis, Giulia De; Toniolo, Chiara; Pasqua, Gabriella

doi:10.1080/14786419.2019.1610960

Cited by 27 publications

(26 citation statements)

References 30 publications

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“…The presence of antifungal substances in the extracts could be responsible for the observed inhibition of radial growth, as well as possible inhibition of spore germination in vitro. This agrees with earlier reports on antimicrobial plant extracts (Akaeze & Aduramigba-Modupe, 2017;Dhaliwal et al, 1990;Enikuomehin, 1998;Giordani et al, 2020). Rice husk extract was the most effective of all the botanicals tested, followed by Azadirachta indica.…”

Section: A Indica D Benthamianus Oryza Sativa Z Zanthoxyloidessupporting

confidence: 92%

“…The antimicrobial activities of these extracts may be due to the presence of secondary metabolites such as tannins, alkaloids, saponins or flavonoids Adekunle and Odukoya (2006). In a similar study, Giordani et al (2020) investigated the in vitro antimicrobial properties of extracts obtained from 14 medicinal plants. They observed that the extracts exhibited significant levels of antifungal activities against selected mycopathogens.…”

Section: A Indica D Benthamianus Oryza Sativa Z Zanthoxyloidesmentioning

confidence: 99%

“…Continuous use of these chemicals may pose ecological problems (Adedeji & Aduramigba, 2016;Akaeze & Aduramigba-Modupe, 2017;Enikuomehin & Peters, 2002;Okigbo & Emoghene, 2003). However, some extracts from plants have been reported to possess different antimicrobial metabolites with biocontrol potentials against phytopathogens (Giordani et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

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Management of Fusarium Wilt Disease of Tomato (Solanum lycopersicum L.) Using Selected Plant Extracts

Modupe¹,

Alawiye²,

Adedire³

2021

International Journal of Sustainable Agricultural Research

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is considered the most widespread, prevalent and economically damaging fungal disease of tomato in Nigeria. This study was conducted to isolate and identify fungal pathogens associated with tomato wilt disease, and also evaluate the efficacy of four plant extracts in the management of wilt disease in vitro and in vivo. Two varieties of tomato, Roma VF and UC 80 were used for the biocontrol assay. Four plant extracts, Zanthoxylum zanthoxyloides roots, Distemonanthus benthamianus stems, Azadirachta indica seeds and oryza sativa husk were evaluated against Fusarium oxysporum f. sp. lycopersici. Three concentrations (0.03, 0.04 and 0.05 g/mL) of each extract were investigated using the agar dilution method for radial growth inhibition assay. Of the four plant extracts evaluated, Oryza sativa husk extract was the most effective in inhibiting the growth of Fusarium oxysporum, both in vitro and in vivo. Rice husk extract (0.05 g/mL) had the highest inhibition rate (100%), followed by A. indica extract (80.32%) at 0.05 g/mL level of concentration, while Z. zanthoxyloides and D. benthamianus had the inhibition rates of 71.83% and 61.41% respectively, at 0.04 g/mL. Tomato plants treated with rice husk extract (0.05 g/mL) had the least wilt severity scores of 1.25 and 1.50 for both UC 80 and Roma VF varieties, respectively. Rice husk extract was the most effective against Fusarium wilt for both varieties and could serve as an alternative to synthetic chemicals in controlling F. oxysporum f. sp. lycopersici. Contribution/Originality:The primary contribution of this research investigation is establishing the retention of significant antifungal activities in the aqueous extracts of Zanthoxylum zanthoxyloides roots, Distemonanthus benthamianus stems, Azadirachta indica seeds and oryza sativa husk, for the biocontrol of tomato-wilt caused by Fusarium oxysporum f. sp. lycopersici.

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Section: A Indica D Benthamianus Oryza Sativa Z Zanthoxyloidessupporting

confidence: 92%

Section: A Indica D Benthamianus Oryza Sativa Z Zanthoxyloidesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Management of Fusarium Wilt Disease of Tomato (Solanum lycopersicum L.) Using Selected Plant Extracts

Modupe¹,

Alawiye²,

Adedire³

2021

International Journal of Sustainable Agricultural Research

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“…It is well known that essential oils have antimicrobial and antifungal activity. However, these properties could be ascribed to other compound classes besides terpenes, such as flavones, as demonstrated in S. scordifolia (Giordani et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

“…However, the antioxidant action of the ethanol extract of aerial parts and roots is known (Grzegorczyk‐Karolak et al, 2019), together with the inhibitory effect of the methanol extract on the tyrosinase enzyme (Revoltella et al, 2019) and the antifeedant, cytotoxic, chemo‐sensitizing and neuroprotective properties of some molecules isolated from the plant (Bozov & Georgieva, 2017; Gao et al, 2017; Jia et al, 2019). In addition, S. scordifolia L. methanolic extracts, obtained at room temperature, showed activity against Candida spp., Malassezia furfur and other dermatophytes (Giordani et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

A novel study approach on Scutellaria altissima L. cultivated at the Ghirardi Botanic Garden (Lombardy, Italy)

et al. 2020

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Within an Open Science project, research was carried out to describe to the public of the Ghirardi Botanic Garden (BS, Lombardy, Italy) the invisible features of plants. This work is dedicated to Scutellaria altissima L. (Lamiaceae). Micromorphological, histochemical and phytochemical investigations were conducted on the vegetative and reproductive organs to correlate the structures involved in the emission of substances and their unique productivity. This work reports volatile organic compound (VOC) profiles of leaves and flowers and the composition of essential oil (EO) obtained from aerial parts of plants cultivated in Italy that have never been described before. Three morphotypes of glandular trichomes were observed: peltate, short‐stalked capitate and long‐stalked capitate. Peltate trichomes were the main producers of terpenes, short‐stalked capitates of polysaccharides and long‐stalked capitates of terpenes and polyphenols. The leaf VOC profile showed heterogeneous composition, with non‐terpene derivatives as the major chemical class (71.04%), while monoterpene hydrocarbons represented almost the totality of the flower (99.73%). The leaf presented a higher number of total (37 versus 11) and exclusive (33 versus 7) compounds. (Z)‐3‐Hexenol acetate was most abundant in the leaf and (E)‐β‐ocimene in the flower. Four common compounds were detected: β‐pinene, β‐caryophyllene, γ‐muurolene and germacrene‐D. The EO contaied 21 compounds, dominated by β‐caryophyllene, linalool and hexahydrofarnesyl acetone. This research allowed us to correlate morphotypes of the secretory structures with the production of secondary metabolites, with the aim of providing the public of the Ghirardi Botanic Garden with a dedicated iconographic approach, which accounts for olfactory perception linked to S. altissima.

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Pharmacological Activities of Rhododendron afghanicum; an Endemic Species of Khyber Pakhtunkhwa, Pakistan

Alam,

Ahmad,

Ahmad

et al. 2023

Chemistry & Biodiversity

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Majority of different kinds of metabolites having therapeutic characteristics are thought to be stored in medicinal plants. So, the present study was aimed to explore the crude extract of leaves and stem of R. afghanicum for phytochemical screening and various pharmacological activities. Toxicological studies at 100 mg/kg showed 60 % mortality where its safe dose level was 90 mg/kg. Phytochemical screening revealed the presence of alkaloids, glycosides, flavonoids and tannins in both extracts. Bacterial strains were susceptible to (RLEt) and (RLM) crude extracts except Staphylococcus aureus. RSM showed maximum anti‐inflammatory activity (20.16 %) followed by RSEt (20.14 %) where lowest activity was displayed by RLEt (18.46 %). Phytotoxic activity showed a substantial dose‐dependent phyto‐inhibition of Lemna minor. An outstanding cytotoxic potential was displayed with LD50 values of 9.46 and 13.03 μg/ml in both stem extracts. RLEt demonstrated a dose‐dependent pain relief at 30, 60 and 90 mg/kg which was 31 %, 40 % and 52 % respectively. A considerable spasmolytic action was observed by the shrinkage of jejunum muscle in albino mice. RLEt at 1000 ppm showed (17 mm) and RLM at 1000 ppm showed (16 mm) zone of inhibition against Aspergillus niger. These findings support and corroborate the traditional applications of R. afghanicum for treating digestive, analgesic and inflammatory ailments.

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Antifungal activity of Mongolian medicinal plant extracts

Cited by 27 publications

References 30 publications

Management of Fusarium Wilt Disease of Tomato (Solanum lycopersicum L.) Using Selected Plant Extracts

Management of Fusarium Wilt Disease of Tomato (Solanum lycopersicum L.) Using Selected Plant Extracts

A novel study approach on Scutellaria altissima L. cultivated at the Ghirardi Botanic Garden (Lombardy, Italy)

Pharmacological Activities of Rhododendron afghanicum; an Endemic Species of Khyber Pakhtunkhwa, Pakistan

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