Antifungal activity of Coriandrum sativum essential oil, its mode of action against Candida species and potential synergism with amphotericin B

Silva, Filomena; Ferreira, Susana; Duarte, Andreia; Mendonça, Dina I.M.D. de; Domingues, Fernanda

doi:10.1016/j.phymed.2011.06.033

Cited by 152 publications

(97 citation statements)

References 30 publications

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“…Relatively little research concerned the mechanisms of their action, such as impact on the virulence factors [42,43]. This report includes results proving the influence of P. dioscoridis extract on possible mechanisms reported to be relevant for Candida pathogenesis, namely extracellular production of various enzymes.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Pluchea dioscoridis leaf extract against pathogenic Candida albicans

El-Zawawy

Hafez

2017

J Infect Dev Ctries

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Introduction: This study aimed to evaluate the efficacy of Pluchea dioscoridis leaf extract on growth, survival, morphogenesis, and virulence gene expression of Candida albicans. Methodology: Anticandidal activity was studied using the hole-plate method against four pathogenic C. albicans strains from clinical isolates. The effect of the extract on the growth profile of the yeast was also examined via a time-kill assay. Microscopic observations using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were made to determine the major alterations in the microstructure of C. albicans. Quantitative changes in phospholipase, hemolysin, and secreted aspartyl proteinase (SAP1 and SAP10) genes expression as virulence factors were analyzed using real-time polymerase chain reaction (RT-PCR). Results: The extract exhibited high anticandidal activity, with the zones of inhibition between 0.5 and 6 cm, and recorded a minimum inhibitory concentration (MIC) value of 30 mg/mL. The time-kill study suggested that the extract possessed yeasticidal properties at higher concentrations and eradicated the growth of yeast cells. The SEM and TEM micrographs exhibited major abnormalities that occurred on the yeast cells after being exposed to the extract, resulting in complete alterations in their morphology and collapse of the cells beyond repair. At MIC concentration, phospholipase, proteinase, and hemolysin gene expression was reduced to 90%, 70%, 90% for SAP1, and 40% for SAP10,respectively, compared to that obtained from untreated C. albicans, as demonstrated by quantitative reverse transcription (RT)-PCR analysis. Conclusions: The P. dioscoridis leaf extract may be an effective anticandidal agent to treat pathogenic yeast infections.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Pluchea dioscoridis leaf extract against pathogenic Candida albicans

El-Zawawy

Hafez

2017

J Infect Dev Ctries

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“…It is very important to underline that the use of plants and other botanical preparations are used, since ancient times, by primitive societies, due to healing properties and therapeutic and psychotherapeutic benefits. It is important to address the fact that plants are widely used to obtain a large variety of drugs, being used in folk medicine for a long time [26][27][28][29][32][33][34][35]. Concerning that plants represent an economic, easily and which are accessible for all of people, they can be used into a variety of diseases, constituting an excellent source of biomolecules able to act like natural antifungal agents and, at the same time, to encourage the search for other alternative treatments.…”

Section: Therapeutic Approachmentioning

confidence: 99%

Candidiasis: Predisposing Factors, Prevention, Diagnosis and Alternative Treatment

et al. 2014

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SUMMARYCandidiasis is the most common opportunistic yeast infection. Candida species and other microorganisms are involved in this complicated fungal infection, but Candida albicans continues to be the most prevalent. In the past two decades, it has been observed an abnormal overgrowth in the gastrointestinal, urinary and respiratory tracts, not only in immunocompromised patients, but also related to nosocomial infections and even in healthy individuals. There is a widely variety of causal factors that contribute to yeast infection which means that candidiasis is a good example of a multifactorial syndrome. Due to rapid increase in the incidence of these infections, this is the subject of numerous studies. Recently, the focus of attention is the treatment and, above all, the prevention of those complications. The diagnosis of candidiasis could become quite complicated. Prevention is the most effective "treatment", much more than eradication of the yeast with antifungal agents. There are several aspects to consider in the daily routine that can provide a strength protection. However, a therapeutic approach is necessary when the infection is established and, therefore, other alternatives should be explored. This review provides an overview on predisposition factors, prevention and diagnosis of candidiasis, highlighting alternative approaches for candidiasis treatment.

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“…Similarly, Çabuk et al (2003) reported that linalool negatively affected Escherichia coli, Pseudomonasaeruginosa, Salmonella typhimurium, Staphylococcus aureus, Clostridium botulinum and Clostridium perfringens intestinal populations. Silva et al (2011) evaluated the antibacterial action of coriander essential oil against gram-positive and gram-negative bacteria using flow cytometry and suggested that the primary mechanism of action of coriander essential oil is membrane damage. In accordance with our study, Cross et al (2007) and Kirkpinar et al (2011) showed that supplementation of some essential oils (thyme, oregano, marjoram, rosemary, or yarrow) had no effect on lactic acid bacteria of broiler.…”

Section: Gut Microbiotamentioning

confidence: 99%

Effects of Coriander Essential Oil on the Performance, Blood Characteristics, Intestinal Microbiota and Histological of Broilers

Ghazanfari

Mohammadi

Moradi

2015

Rev. Bras. Cienc. Avic.

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Present study was conducted to investigate the effects of the dietary supplementation of coriander oil on broiler performance, blood characteristics, microbiota, and small intestine morphology measurements. A number of one-day-old broiler chickens (Ross 308) were allocated to five treatments, with four replicates according to a completely randomized design (CRD). Birds were offered either a cornsoybean meal basal diet (control), or the basal diet supplemented with 600

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Antifungal activity of Coriandrum sativum essential oil, its mode of action against Candida species and potential synergism with amphotericin B

Cited by 152 publications

References 30 publications

Efficacy of Pluchea dioscoridis leaf extract against pathogenic Candida albicans

Efficacy of Pluchea dioscoridis leaf extract against pathogenic Candida albicans

Candidiasis: Predisposing Factors, Prevention, Diagnosis and Alternative Treatment

Effects of Coriander Essential Oil on the Performance, Blood Characteristics, Intestinal Microbiota and Histological of Broilers

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