Antifungal activity and hair growth stimulation of purple sweet potato leaf fraction (Ipomoea batatas (L.) Lamk) and its molecular mechanism through androgen receptor inhibition
Fery Indradewi Armadany,
Iyan Sopyan,
Resmi Mustarichie
et al.
Abstract:Alopecia presented a global challenge, spurring the search for new treatments. This study evaluated Ipomoea batatas leaf extracts for their ability to stimulate hair growth and inhibit Malassezia furfur. Secondary metabolites were identified and assessed for their potential to inhibit androgen receptors (AR) via LC-MS/MS and in silico analysis. The hair tonic formulation was optimized using a D-optimal mixture design to improve physicochemical properties. The plant’s extracts and fractions exhibited strong ant… Show more
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