Antifungal Activities of the Leaves of Baphia Nitida, Cassia Alata, Ficus Exasperata and Gossypium Arboreum

Okafor, J. I.; Eze, EA; Njoku, OU

doi:10.4314/njnpm.v5i1.11728

Nigerian Journal of Natural Products and Medicine

2001

DOI: 10.4314/njnpm.v5i1.11728

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Antifungal Activities of the Leaves of Baphia Nitida, Cassia Alata, Ficus Exasperata and Gossypium Arboreum

J. I. Okafor

EA Eze

OU Njoku

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“…In Nigeria, the young leaves are prescribed as a common anti-ulcer remedy. Various pharmacological actions, such as anti-ulcer, anti-diabetic, lipid lowering and antifungal activities have been also described for F. exasperata [2][3][4][5]. The plant was shown, however, to posses no antibacterial properties [6].…”

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Volatile Constituents of Ficus Exasperata Leaves

Sonibare

Ogunwande

Walker

et al. 2006

Natural Product Communications

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The composition of the volatile leaf oil of Ficus exasperata Vahl (Moraceae) is reported. The oil was obtained by hydrodistillation and analyzed for its constituents by means of gas chromatography-mass spectrometry (GC-MS). The oil is comprised of terpenoids and aliphatic compounds. The quantitatively significant compounds were 1,8-cineole (13.8%), (Ε)-phytol (13.7%) and p-cymene (11.4%). In addition, all other compounds were present above 2%. The oil shows no antibacterial activity against the tested organisms (MIC 625ppm).

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confidence: 99%

Volatile Constituents of Ficus Exasperata Leaves

Sonibare

Ogunwande

Walker

et al. 2006

Natural Product Communications

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Antimicrobial And Antioxidant Activities Of Some Nigerian Medicinal Plants

Aladesanmi

Iwalewa²,

Adebajo³

et al. 2008

Afr. J. Trad. Compl. Alt. Med.

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Ten Nigerian plants suggested from their ethnomedical uses to possess antimicrobial and antioxidant activities were studied for their anti-microbial and anti-oxidant properties. Antimicrobial activity was tested against Escherichia coli NCTC 10418, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Candida albicans, Candida pseudotropicalis and Trichophyton rubrum (clinical isolate). Trichilia heudelotti leaf extract showed both antibacterial and antifungal activities and was the most active against all the strains of bacteria tested. Boerhavia diffusa, Markhamia tomentosa and T. heudelotti leaf extracts inhibited the gram negative bacteria E.coli and P. aeruginosa strains whereas those of M. tomentosa, T. heudelotti and Sphenoceutrum jollyamum root inhibited at least one of the fungi tested. At a concentration of 312 µg/ml, hexane and chloroform fractions of T. heudelotti extract inhibited 6 and 14% of the fifty mult-idrug resistant bacteria isolates from clinical infectins, respectively. At ≤ 5mg/ml, the CHCl 3 (64%) and aqueous (22%) fractions of T. heudelotti and those of CHCl 3 (34%) and EtOAC (48%) of M. tomentosa gave the highest inhibition that was stronger than their corresponding methanol extracts. The corresponding EC 50 of the extracts on M. acuminata, T. heudelotti, E. senegalensis and M. tomentosa were 4.00, 6.50, 13.33, and 16.50 ig/ml using the TLC staining and 1,1-dipheyl-2-picry-hydrazyl (DPPH) free radical scavenging assay. Therefore, leaf extracts of M. tomentosa and T. heudelotti, especially the latter, possess strong antimicrobial and antioxidant activities and should be further investigated. These activities justified the ethnomedical uses of these plants.

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Antifungal Activities of the Leaves of Baphia Nitida, Cassia Alata, Ficus Exasperata and Gossypium Arboreum

Cited by 2 publications

References 0 publications

Volatile Constituents of Ficus Exasperata Leaves

Volatile Constituents of Ficus Exasperata Leaves

Antimicrobial And Antioxidant Activities Of Some Nigerian Medicinal Plants

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