Antifungal action of Pichia anomala against aflatoxigenic Aspergillus flavus and its application as a feed supplement

Abstract

P. anomala could be strongly recommended as a biocontrol agent against A. flavus which contaminates animal feed. Furthermore, the application of yeast cells, as a feed additive, proved its efficiency for escalating protein content and enhancing animal performance.

The action mechanism and biocontrol potentiality of novel isolates of Saccharomyces cerevisiae against the aflatoxigenic Aspergillus flavus

“…In a similar study, Tayel et al . () reported that the hyphae of A. flavus were totally penetrated and destroyed by the parasitic and lytic actions of the antagonistic yeast. This could be proposed as a possible mode of action of this biocontrol yeast in suppressing fungal growth and this might be attributed to competition for space or for a specific growth‐limiting factor and production of substances that affect hyphae integrity (Cubaiu et al .…”

“…Moreover, during their growth they might produce mycotoxins and other secondary metabolites which are harmful to human and animal health (Tayel et al . ). Mycotoxins are health‐damaging metabolites which can be carcinogenic, hepatotoxic, teratogenic or immunosuppressing for human and animals (Muñoz et al .…”

“…The consumption of foods contaminated by aflatoxin B 1 increase risk of developing hepatocellular carcinoma (Tayel et al . ).…”

“…The growth and survival of these fungi cause losses in dry matter, quality and economic value of the stored food and feed products (Amaike and Keller 2011;Roze et al 2013). Moreover, during their growth they might produce mycotoxins and other secondary metabolites which are harmful to human and animal health (Tayel et al 2013). Mycotoxins are health-damaging metabolites which can be carcinogenic, hepatotoxic, teratogenic or immunosuppressing for human and animals (Muñoz et al 2010).…”

“…Among these aflatoxins, the most important and dangerous is aflatoxin B 1 because it is produced in high concentrations and was identified to be the most potent hepatotoxin and carcinogen (Adhikari et al 2016). The consumption of foods contaminated by aflatoxin B 1 increase risk of developing hepatocellular carcinoma (Tayel et al 2013).…”