Antifertility potential of the ethanolic extract of Caesalpinia pulcherrima Linn. leaves

Kumar, Sunil; Singh, Jasbir; Baghotia, Anupama; Mehta, Vineet; Thakur, Vikas; Choudhary, Manjusha; Verma, Surender; Kumar, Dinesh

doi:10.1016/s2305-0500(13)60125-6

Cited by 10 publications

(4 citation statements)

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“…in mice: ethanol extracts of leaves of Casimiroa edulis [ 105 ] and Cnidoscolus chayamansa [ 106 ], ethanol extracts of aerial parts of Moussonia deppeana [ 107 ], Equisetum hyemale [ 93 ], and Ruta chalepensis [ 108 ], as well as methanol extracts of leaves of Chenopodium ambrosioides [ 109 ] and Rauvolfia tetraphylla [ 110 ]. The same pattern was also shown in aqueous extract of Cuphea aequipetala aerial parts [ 111 ], ethanol extract of Plumeria rubra flowers [ 112 ], aqueous extract of Larrea divaricata leaves [ 113 ], ethanol extract of Caesalpinia pulcherrima leaves and bark [ 114 , 115 ]. aqueous extract of Euphorbia prostrata whole plant [ 116 ], aqueous-methanol extract of Ceiba pentandra leaves [ 117 ], petroleum ether, chloroform, and methanol extracts of Gelsemium sempervirens roots [ 118 ], acetone extract of Capsicum annum fruits [ 119 ], and aqueous and ethanol extract of Scoparia dulcis leaves and whole plant [ 120 , 121 ].…”

Section: Toxicologysupporting

confidence: 58%

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

Alonso-Castro

Domínguez

Ruiz-Padilla

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of Chenopodium ambrosioides, Argemone mexicana, and Thevetia peruviana. In most of the cases, the principle of the plant responsible for the toxicity is unknown. There is limited information about the toxicity of medicinal plants used in Mexico, Central America, and the Caribbean. More toxicological studies are necessary to contribute information about the safe use of the medicinal plants cited in this review.

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Section: Toxicologysupporting

confidence: 58%

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

Alonso-Castro

Domínguez

Ruiz-Padilla

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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“…The stem and bark are also reported to have an emmenagogue effect. An in vivo study of female albino mice [ 166 ] showed the anti-implantation activity of the ethanolic extract of the leaves of this plant, supporting its traditional use as an antifertility agent. This in vivo antifertility effect was also observed with the use of the alcoholic extract of the bark in Wistar rats [ 175 ].…”

Section: Resultsmentioning

confidence: 98%

Female naturalists and the patterns of suppression of women scientists in history: the example of Maria Sibylla Merian and her contributions about useful plants

Mariath

Baratto

2023

J Ethnobiology Ethnomedicine

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Background This work reunites many women naturalists who registered knowledge about native flora in scientific expeditions around the globe between the seventeenth and nineteenth centuries. Since male naturalists are more recognized in this period of time, we aimed to list female naturalists that published plant descriptions and observations, focusing on the work of Maria Sibylla Merian and to analyze her trajectory as an example to discuss the patterns of the suppression of women scientists. A second aim was to inventory the useful plants described in Maria Sibylla’s Metamorphosis Insectorum Surinamensium and find pharmacological evidence about the traditional uses described for those plants cited as medicinal and toxic. Methods A survey of female naturalists was carried out by searching information in Pubmed, Scielo, Google Scholar and Virtual Health Library. Once Maria Sibylla published her book Metamorphosis Insectorum Surinamensium by her own, without male co-authors, and also this book is one of the only to have text and illustrations altogether and there are reports indicating information on useful plants in this work, she and her book were chosen as subject of this research. All the information was tabulated by dividing the plants into food, medicinal, toxic, aromatic or other uses. Finally, with the combinations of the scientific name of medicinal and toxic plants with information about their popular uses, a search was carried out in databases in order to indicate current pharmacological studies that reported evidences about the traditional uses described. Results We found 28 women naturalists who participated in scientific expeditions or trips, or in a curiosity cabinet, or who were collectors of Natural History between the seventeenth and nineteenth centuries. All these women illustrated botanical species and/or recorded their everyday or medicinal use or reported their observations in the form of a published work, letters or diaries. Also, the trajectory of Maria Sibylla Merian revealed that her scientific relevance has been neglected from the eighteenth century by mechanisms of suppression, most of the time by male depreciation, which can be seen as a pattern for suppression of women in science. However, Maria Sibyllas’ contributions have been valued again in the twenty-first century. In Maria Sibylla’s work, 54 plants were identified, 26 of them used for food, 4 of them aromatic, 8 medicinal, 4 toxic and 9 other uses. Conclusion This study evidences that there are female naturalists whose work could be an important source for ethnopharmacological studies. Researching about women scientists, talking about them and highlighting the gender bias present in the scientific academy about the way the history of science is told is essential for the construction of a more diverse and richer scientific academy. The traditional use of 7 of 8 medicinal plants and 3 of 4 toxic plants reported was correlated with pharmacological studies, highlighting the importance of this historical record and its potential to direct strategic research in traditional medicine.

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“…Linn 43,44 Tabernaemontana divaricate 45,46 Jatropha gossypifolia 47 Alstonia scholaris 48 Curcuma longa 49 Piper betel 50 Cordia dichotoma 51 Hymenocardia acida 52 Heliotropium indicum 53 Rivea hypocratiriformis 77 Asparagus africanus 78…”

Section: Caesalpina Pulcherrimamentioning

confidence: 99%

Untitled

2022

IJPSR

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Along with increasing availability and utilization of contraception, it is also important to confirm that the effects of contraception use on resumption of fertility after discontinuation and serious adverse effects produced by synthetic steroidal contraceptives remained a major problem. However, current evidence on resumption of fertility after contraception use is inconclusive, and practically fertility after termination of contraception remains a big concern for women who are using contraception. This fear poses a negative impact on utilization and continuation of contraception. Therefore, the development of new fertility regulating drug from medicinal plants is an attractive proposition. So available reports and identifying the associating factors are important for designing a strategy to overcome the problem. Methods: The review is conducted through a systematic literature search of research articles. Few bibliographic databases and libraries: Pub Med/Medline, Global Health Database, Science direct, Embase, the Cochrane Library were used. Results: The review of different database studies that enrolled profiles of various medicinal plants used for contraception was analyzed. Conclusion and Recommendation:Contraceptive use, regardless of its duration and type, does not have a (negative) effect on the ability of women to conceive following termination of use, and it does not significantly delay fertility, but the serious adverse effects associated with synthetic steroidal contraceptives are definite and significant. So, it can be recommended to develop contraceptives from herbal medicinal plants with the least toxicity and more efficacy.INTRODUCTION: Anti-fertility agents are drugs that control fertility 1 and are also called oral contraceptives. These drugs affect and are involved in the menstrual cycle and ovulation in females. Estrogen and progesterone in combined form are QUICK RESPONSE CODE

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Antifertility potential of the ethanolic extract of Caesalpinia pulcherrima Linn. leaves

Cited by 10 publications

References 4 publications

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

Female naturalists and the patterns of suppression of women scientists in history: the example of Maria Sibylla Merian and her contributions about useful plants

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