Abstract:This study evaluated the antidiabetic effect of the ethanolic combined extract of Ocimum gratissimum and Vernonia amygdalina (OGVA) in streptozotocin-induced diabetic rats. The phytochemical content and safety level of OGVA in mice were assayed using standard methods and Lorke’s model of toxicity study, respectively. Graded OGVA doses were administered orally in streptozotocin-induced diabetic rats for 21 days. Indices of diabetes, oxidative stress, and tissue histology were assessed using biochemical kits and… Show more
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