Antidiabetic effect of a newly identified component of Opuntia dillenii polysaccharides

Zhao, Longyan; Lan, Qing-Hua; Huang, Zhenchi; Ouyang, Lejun; Fu-hua, Zeng

doi:10.1016/j.phymed.2011.01.001

Cited by 90 publications

(52 citation statements)

References 38 publications

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“…These results revealed that EAF might be antidiabetic by regulating gene expression and pancreas function. Wolff (1993) and Zhao et al (2011) report increased lipid peroxides and decreased antioxidant enzymes in individuals of diabetes mellitus. Similar results were observed in El-Missiry (El-Missiry and El-Gindy, 2000) and the present study.…”

Section: Discussionmentioning

confidence: 99%

Antidiabetic and antihyperlipidemic activities of Forsythia suspensa (Thunb.) Vahl (fruit) in streptozotocin-induced diabetes mice

Zhang

Feng

Chen

et al. 2016

Journal of Ethnopharmacology

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Section: Discussionmentioning

confidence: 99%

Antidiabetic and antihyperlipidemic activities of Forsythia suspensa (Thunb.) Vahl (fruit) in streptozotocin-induced diabetes mice

Zhang

Feng

Chen

et al. 2016

Journal of Ethnopharmacology

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“…Mangifera indica 3β-taraxerol [91] 17 Olea europaea Triterpenoids [98] 18 Ophiopogon japonicas Polysaccharide [99] 19 Opuntia dillenii Polysaccharides [100] 20 Panax ginseng Ginsenosides [101,102] 21 Pongamia pinnata Karanjin [106] 22 Prosopis glandulosa Diavite™ [108] 23…”

Section: Echinacea Purpureamentioning

confidence: 99%

“…[87] Additionally, some studies have demonstrated the role of polysaccharides isolated from Ophiopogon japonicas and Opuntia dillenii in improving insulin resistance in type 2 diabetes mellitus. [99,100] Ginsenosides from Panax ginseng have been demonstrated to improve insulin sensitivity in Zucker diabetic fatty rats by marking the effects on the expression of genes involved in PPAR actions and triglyceride metabolism. [101] Karanjin isolated from Pongamia pinnata has been shown to exert antihyperglycemic effect.…”

Section: Vaccinium Vitis-idaeamentioning

confidence: 99%

Antidiabetic plants improving insulin sensitivity

Eddouks¹,

Bidi²,

Bouhali³

et al. 2014

Journal of Pharmacy and Pharmacology

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Background Globally, the prevalence of diabetes mellitus is increasing at an alarming rate. This chronic pathology gravely troubled the human health and quality of life. Both insulin deficiency and insulin resistance are involved in the pathophysiology of diabetes mellitus. Moreover, insulin resistance is being diagnosed nowadays in a growing population of diabetic and obese patients, especially in industrialized societies. There are lots of conventional agents available to control and to treat diabetes, but total recovery from this disorder has not been reported up to this date. Plants provided a potential source of hypoglycemic drugs and are widely used in several traditional systems of medicine to prevent diabetes. A few reviews with less attention paid to mechanisms of action have been published on antidiabetic plants. Objectives The present review focuses on the various plants that have been reported to be effective in improving insulin sensitivity associated with diabetes. Key findings In this work, an updated systematic review of the published literature has been conducted to review the antidiabetic plants improving insulin sensitivity and 111 medicinal plants have been reported to have a beneficial effect on insulin sensitivity using several in-vitro and in-vivo animal models of diabetes. Conclusion The different metabolic and cellular effects of the antidiabetic plants improving insulin sensitivity are reported indicating the important role of medicinal plants as potential alternative or complementary use in controlling insulin resistance associated with diabetes mellitus.

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“…24 Opuntia dillenii (erect prickly pear, nopal estricto) polysaccharides lowered blood glucose without raising serum insulin in diabetic rodents, apparently by reducing liver oxidation and protecting insulin sensitivity in peripheral tissues. 25 Most studies with prickly pear have found it safe for moderate-term use. There is one case study suggesting that a combination of prickly pear pads, metformin, and glipizide could cause hypoglycemia.…”

Section: Prickly Pearmentioning

confidence: 99%

Herbs for Diabetes: Update—Part 2

Yarnell¹

2015

Alternative and Complementary Therapies

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This article continues a review of herbal medicines for diabetes mellitus (DM) begun in the prior issue of this Journal. The research on Momordica charantia (bitter melon) fruit for diabetes mellitus (DM) published since 2005 is reviewed. Vegetable insulin derived from the seeds of bitter melon is discussed. Research on, and use of, Opuntia spp. (prickly pear) fruit and pad for DM since 2000 is reviewed. A thorough discussion of Trigonella foenum-graecum (fenugreek) seed and Aloe vera (aloe) gel, both relatively well-studied agents, is included.Several less well-documented but intriguing herbal antidiabetics, including Capparis spinosa (capers) fruit, Juglans regia (English walnut) leaf, Rauvolfia vomitoria (African snakeroot) root, Citrus aurantium (bitter orange) peel, and Salvia officinalis (sage) leaf are reviewed.

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Antidiabetic effect of a newly identified component of Opuntia dillenii polysaccharides

Cited by 90 publications

References 38 publications

Antidiabetic and antihyperlipidemic activities of Forsythia suspensa (Thunb.) Vahl (fruit) in streptozotocin-induced diabetes mice

Antidiabetic and antihyperlipidemic activities of Forsythia suspensa (Thunb.) Vahl (fruit) in streptozotocin-induced diabetes mice

Antidiabetic plants improving insulin sensitivity

Herbs for Diabetes: Update—Part 2

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