Antidiabetic Compounds in Stem Juice from Banana

Nguyen, Dong Van; Zachariasova, Alena; Spurna, Klara; Hricko, Jiri; Huong, Phung Thanh; Viktorová, Jitka; Stranska-Zachariasova, Milena; Hajšlová, Jana; Ruml, Tomáš

doi:10.17221/172/2017-cjfs

Cited by 26 publications

(6 citation statements)

References 31 publications

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“…The extracts were diluted with methanol to concentrations from 0.001 mg/mL to 0.1 mg/mL. To 20 µL of the diluted extract, we added 60 µL of PBS and 10 µL of the α-amylase with a concentration of 0.8 mg/mL and incubated at room temperature (20 • C for 10 min) according to [23]. Afterwards, 10 µL of substrate CNPG3 (2-chloro-p-nitrophenyl-α-D-maltotrioside, 6.6 mg/mL) was added; after that, the absorbance (400 nm) was immediately recorded in 1 min intervals for 10 min.…”

Section: Antidiabetic Activity Assaymentioning

confidence: 99%

In Vitro Comparison of the Bioactivities of Japanese and Bohemian Knotweed Ethanol Extracts

Pogačnik

Bergant

Skrt

et al. 2020

Foods

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Knotweed is a flowering plant that is native to temperate and subtropical regions in the northern hemisphere. We evaluated Japanese (Reynoutria japonica Houtt.) and Bohemian (Fallopia x bohemica) knotweed rhizome and flower ethanol extracts and compared them in terms of their biological activities. The specific polyphenols were identified and quantified using HPLC/DAD, and the antioxidant activity was determined using 2,2-diphenly-1-picrylhydrazyl (DPPH) and cellular antioxidant capacity assays. The anticancer activity was evaluated as the difference between the cytotoxicity to cancer cells compared with control cells. The antimicrobial activity was determined using bacteria and yeast. The antidiabetic activity was tested as the ability of the extracts to inhibit α-amylase. Both rhizome extracts were sources of polyphenols, particularly polydatin and (−)-epicatechin; however, the cellular assay showed the highest antioxidant capacity in the flower extract of F. bohemica. The PaTu cell line was the least sensitive toward all knotweed extracts. The flower extracts of both species were less toxic than the rhizomes. However, the activity of the tested extracts was not specific for cancer cells, indicating a rather toxic mode of action. Furthermore, all used extracts decreased the α-amylase activity, and the rhizome extracts were more effective than the flower extracts. None of the extracts inhibited bacterial growth; however, they inhibited yeast growth. The results confirmed that rhizomes of Reynoutria japonica Houtt. could become a new source of bioactive compounds, which could be used for the co-treatment of diabetes and as antifungal agents.

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Section: Antidiabetic Activity Assaymentioning

confidence: 99%

In Vitro Comparison of the Bioactivities of Japanese and Bohemian Knotweed Ethanol Extracts

Pogačnik

Bergant

Skrt

et al. 2020

Foods

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“…According to (Zaini, et al, 2022), bioactives found in natural foods have a significant potential for use in the food sector or as therapeutic agents for other metabolic illnesses. (Kalita, et al, 2016;Nguyen, et al, 2017;Indrawati, et al, 2022;Abdel-Naime et al, 2020).…”

Section: Resultsmentioning

confidence: 99%

ANALGETIC EFFECT OF COMBINATION 3:2:1 GEL EXTRACT Ageratum conyzoides Mussaenda frondosa) AND Curcuma domestica of Staphylococcus aureus INFECTED POST PARTUM MICE

Hujjatusnaini,

Nada,

Jumrodah

et al. 2023

jika

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The lack of knowledge about Ageratum conyzoides, Mussaenda frondosa, and Curcuma domestica as alternative medicines for treating postpartum infections, because there is still little research and documentation being carried out. Therefore, this research is expected to prove in vivo in order to know the analgesic effect of the combination formulation 3:2:1 extracts of Ageratum conyzoides, Mussaenda frondosa, and Curcuma domestica as therapy for post-partum infections. The research method used a true experimental post-test only control-group design, with 36 pregnant female mice as the test object. Ageratum conyzoides leaves, Mussaenda frondosa, and Curcuma domestica were prepared in a 3:2:1 formulation, with design levels of 40%, 60% and 80%. Analgesic-effect data were analyzed using the ANAVA statistical method and Duncan's test with a significant level of 1%. The results of the analgesic effect were obtained from the average number of S.aureus colonies and the vaginal mucosal fluid secretion index of mice infected with S.aureus. The results showed that the combination formulation of 3:2:1 extracts with a concentration of 30% had a significant effect on growth in S.aureus at a significant level of 1%. It was concluded that the 3:2:1 combination formulation can be recommended as the most effective in inhibiting infection S.aureus.

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“…Furthermore, ferulic acid was successfully determined among other bioactive compounds in stem juices from banana plants using a tandem high-resolution mass spectrometry (UHPL-HRMS/MS) method. An investigation into variations in the occurrence of potentially antidiabetic compounds revealed signi cant differences in the concentration of ferulic acid based on the origin of the bananas, underscoring the in uence of growth conditions on its presence (Nguyen et al 2017). Phenolic compound pro ling in various banana varieties was also conducted through two analytical methods, HPLC-ESI-HR-MS and HPLC-DAD.…”

Section: Resultsmentioning

confidence: 99%

Ambient mass spectrometry imaging of banana (Musa spp.) tissue with infrared laser-based selected reaction monitoring

Nizioł,

Misiorek,

Krupa

et al. 2023

Preprint

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In this study, for the first time we present the application of an infrared (IR) laser ablation-remote-electrospray ionization (LARESI) platform coupled to a tandem mass spectrometer (MS/MS) operated in selected reaction monitoring (SRM) mode for targeted metabolite imaging in intact plant tissues. We examined the distribution of specific metabolites in two banana varieties: Red Dacca and Cavendish. To support MSI results, an extensive analysis of banana tissue extracts was conducted using ultra-high-performance liquid chromatography and ultra-high-resolution mass spectrometry (UHPLC-UHRMS). In the Cavendish banana, 12 metabolites were successfully identified, while Red Dacca Bananas were found to contain 16 amino acids. The spatial distribution of some of these compounds found in bananas was presented for the first time. This approach eliminates the need for high vacuum conditions and the pretreatment of biological materials, making it an efficient and promising tool for studying metabolites in plant tissues.

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Antidiabetic Compounds in Stem Juice from Banana

Cited by 26 publications

References 31 publications

In Vitro Comparison of the Bioactivities of Japanese and Bohemian Knotweed Ethanol Extracts

In Vitro Comparison of the Bioactivities of Japanese and Bohemian Knotweed Ethanol Extracts

ANALGETIC EFFECT OF COMBINATION 3:2:1 GEL EXTRACT Ageratum conyzoides Mussaenda frondosa) AND Curcuma domestica of Staphylococcus aureus INFECTED POST PARTUM MICE

Ambient mass spectrometry imaging of banana (Musa spp.) tissue with infrared laser-based selected reaction monitoring

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