Antidiabetic, Antihypertensive and Antioxidant Properties of Grapevine Leaf Extracts Obtained by Ultrasound, Microwave Assisted, and Classical Solvent Extraction

Hayta, Mehmet; İşçimen, Elif Meltem

doi:10.1007/s10341-018-0406-6

Cited by 6 publications

(5 citation statements)

References 37 publications

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“…100% of the amplitude of ultrasound was used for 10 min. Supernatants were collected, freeze-dried, and kept at 4 °C after being centrifuged at 9,000 rpm for 10 min at 20°C ( Hayta and Işçimen, 2018 ). Despite the widespread use of UAE, the technique has two issues which includes uneven ultrasound energy distribution and a power decrease over time ( Ajila et al, 2011 ).…”

Section: Extraction Techniques For the Preparation Of Grape Leaf Extractmentioning

confidence: 99%

“…This has been demonstrated by an increase in Nrf2, one of the key regulators of oxidative stress in cells ( Ha et al, 2021 ). Ultrasound was applied 100% amplitude in extraction of grape leaves through Ultrasound-Assisted Extraction (UAE) ( Hayta and Işçimen, 2018 ). The extraction yield was found to be 13.81%.…”

Section: Extraction Techniques For the Preparation Of Grape Leaf Extractmentioning

confidence: 99%

“…For maximum antioxidant component extraction from grapevine leaves, the ideal microwave conditions were 30% solid/ liquid for 300 s at 300 W of microwave power. After being microwaved, samples were centrifuged at 9,000 rpm for time span of 15 min at temperature of 25 °C and filtered using filter paper and supernatants were collected and stored in storage at −18 °C (Hayta and İşçimen, 2021). The primary benefits of MAE over Soxhlet extraction relate to the sharp decrease in solvent consumption (5 V 100 mL) and extraction duration (40S V 6h) (Chaturvedi, 2018).…”

Section: Microwave-assisted Extractionmentioning

confidence: 99%

“…Microwave-assisted extraction (MAE) was used to identify and quantify the bioactive components found in grape leaves, including gallic and caftaric acids, phytosterols, quercetin-3-glucuronide, quercetin-3-glucoside, and kaempferol-3-rutinoside (Djemaa-Landri et al, 2020). Microwave-assisted extraction (MAE) of grape leaves was performed with a power of 300 W (Hayta and Işçimen, 2021). It was discovered that MAE increases yield, shortens extraction times, and uses less solvent (Reis et al, 2015;Hayta and Işçimen, 2021).…”

Section: Pulsed Electric Field Extractionmentioning

confidence: 99%

“…Microwave-assisted extraction (MAE) of grape leaves was performed with a power of 300 W (Hayta and Işçimen, 2021). It was discovered that MAE increases yield, shortens extraction times, and uses less solvent (Reis et al, 2015;Hayta and Işçimen, 2021). Numerous studies have revealed that quercetin is associated with melanogenesis and offers pharmacological effects such as anti-inflammatory, anti-atherosclerotic, antioxidant, anticancer, and skin protecting qualities.…”

Section: Pulsed Electric Field Extractionmentioning

confidence: 99%

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Valorization of grape (Vitis vinifera) leaves for bioactive compounds: novel green extraction technologies and food-pharma applications

Singh,

Rasane,

Kaur

et al. 2023

Front. Chem.

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Grape leaves, scientifically known as Vitis vinifera, the primary by-product obtained after the processing of grapes, are gathered in enormous amounts and disposed of as agricultural waste. For more sustainable agriculture and better food systems, it is crucial to investigate these byproducts’ nutritional values. The primary bioactive compounds present in grape leaves are quercetin, resveratrol, caffeic acid, kaempferol, and gallic acid, which favour pharmacological effects on human health such as antioxidant, anti-inflammatory, anti-obesity, anti-diabetic, and hepatoprotective. Furthermore, grape leaves extract has been used as a functional ingredient for creating both food and non-food products. The aim of the current review is to review the nutritional and phytochemical composition of various varieties of grape leaves, their health-promoting characteristics and their applications. The study also highlights the various extraction techniques including conventional and non-conventional methods for extracting the various bioactive compounds present in grape leaves. Grape leaves bioactives can be extracted using environmentally safe and sustainable processes, which are in line with the rising demand for eco-friendly and healthful products worldwide. These methods are perfectly suited to the changing needs of both customers and industries since they lessen environmental effect, enhance product quality, and offer financial advantages.

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Section: Extraction Techniques For the Preparation Of Grape Leaf Extractmentioning

confidence: 99%

Section: Extraction Techniques For the Preparation Of Grape Leaf Extractmentioning

confidence: 99%