Antidepressants

Haghparast, Parna; Maroney, Megan; Salwan, A.; Sabbaugh, Adam

doi:10.1016/bs.seda.2021.08.010

Cited by 1 publication

(1 citation statement)

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“…Prophylactic treatment with antiemetics such as ondansetron may help mitigate nausea and vomiting. Some fruit punch-flavored powdered drink mix or some bon-bons could attenuate dysgeusia and probably reduce nausea (35,36).…”

Section: Evidence Based Management Of Aesmentioning

confidence: 99%

Overcoming the myths of esketamine administration: different and not difficult

Buchmayer,

Kasper

2023

Front. Psychiatry

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Intranasal esketamine for treatment-resistant depression has been introduced and approved by the FDA and EMA in 2019 and 2020, respectively. Since then, the administration practices were found different among countries. Major depression has a high impact on many humans lives worldwide and more than a third of treated people are not responding after several treatment attempts. Additional administration with esketamine closed this gap for more than the half of these non-responders. Guidelines for the treatment of major depression recommend starting with add-on esketamine after 2–4 serious attempts of treatment with standard antidepressants (SSRI/SNRI) irrespective of augmentation with others, e.g., second generation antipsychotics or lithium. Thus, intranasal esketamine became an important role in the evidence-based treatment of major depression. The authors review and critically evaluated published articles focusing on preparation, management and observation of intranasal esketamine treatment. There exists a clear recommendation for administrating intranasal esketamine in a medical environment, not limited to a clinical setting for selecting the dose, monitoring the improvements and managing adverse events. The administration of intranasal esketamine is considered as safe during the application itself and long-lasting or severe adverse events during long-term treatment are very rare. Since this is a new approach for treatment application psychiatrists face new different but not difficult treatment procedures compared to prescribing only a medication.

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Section: Evidence Based Management Of Aesmentioning

confidence: 99%