Antidepressant Induced Hyponatremia

Abstract

Electrolyte imbalance is a very common cause as well as comorbidity of hospitalization, especially in elderly individuals. It also enhances the morbidity and mortality in this group of patients. Disorders of sodium balance are the most prevalent types of electrolyte disturbance in clinical settings. Among several etiological factors related to disturbed serum sodium concentration, iatrogenic causes are very common. Antidepressants are noteworthy contributors among the drugs causing reduced plasma sodium concentration and as these drugs are quite commonly used in elderly patients due to high prevalence of depression in this age group, here we discuss about antidepressant induced hyponatremia.