Anticoccidial drugs: Lesion scoring techniques in battery and floor-pen experiments with chickens

Johnson, Joyce; Reid, W. M.

doi:10.1016/0014-4894(70)90063-9

Cited by 1,168 publications

(615 citation statements)

References 19 publications

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“…A post-mortem examination of tissue samples demonstrated inflammatory changes in the cecum (dilated intestinal lumen, mucosal lesions, blood in the intestinal contents) that scored 2 points on the scale proposed by Johnson and Reid (1970). A histopathological analysis revealed the presence of various developmental stages of the coccidia in duodenal, jejunal and cecal mucosa.…”

Section: Methodsmentioning

confidence: 99%

Biochemical parameters in Japanese quails Coturnix coturnix japonica infected with coccidia and treated with Toltrazuril

Sokół

Gesek

Raś-Noryńska

et al. 2015

Polish Journal of Veterinary Sciences

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The activity of aspartate aminotransferase, alanine aminotransferase and lactate dehydrogenase, total protein, albumin and cholesterol levels were determined in the blood serum of Japanese quails infected with coccidia and treated with Baycox (active ingredient: toltrazuril). Lower levels of AST and ALT activity were noted in treated birds regardless of the applied Baycox dose. The biochemical changes observed in the blood serum of Japanese quails point to coccidia-induced damage of digestive system tissues despite an absence of pronounced clinical symptoms. Significantly lower levels of AST activity and higher levels of LDH activity in treated birds indicate that coccidiosis treatment with toltrazuril contributed to the regeneration of digestive system tissues. An insignificant increase in cholesterol levels was noted, whereas the other serum biochemical parameters remained within the reference ranges.

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Section: Methodsmentioning

confidence: 99%

Biochemical parameters in Japanese quails Coturnix coturnix japonica infected with coccidia and treated with Toltrazuril

Sokół

Gesek

Raś-Noryńska

et al. 2015

Polish Journal of Veterinary Sciences

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“…Small intestine lesions were scored on a scale according to severity (Johnson and Reid, 1970). A total of 150 birds were divided into three groups (G1, G2 and G3), each consisting of 50 birds.…”

Section: Onementioning

confidence: 99%

Anticoccidial efficacy of drinking water soluble diclazuril in the control of Eimeria acervulina oocysts on experimentally-infected broiler chickens

Assis

Cury

Luns³

et al. 2012

Arq. Bras. Med. Vet. Zootec.

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The experiment was carried out with 150 Cobb broiler chickens divided into 3 groups with 50 birds each. The groups of infected chickens orally received 1ml of inoculum containing 3x10 3 Eimeria acervulina sporulated oocysts at 12 days of age. Group 1 was kept as a positive control with infected non-medicated birds, group 2 was medicated with diclazuril (1%) with a dose of 1mL/4 L of drinking water for 2 successive days, 5 days after infection, while group 3 was kept as negative control with non-infected and non-medicated birds. Oocysts count per gram of feces, score of macroscopic intestinal lesions and weight gain were evaluated. The group treated with diclazuril showed significant and satisfactory improvement in the assessment criteria when compared to the infected non-medicated group. The results revealed more reduction in the total oocyst count and intestinal lesion score in the medicated than in the infected nontreated group. The results confirmed that (1%) liquid diclazuril is effective to control Eimeria infection.

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“…After sporulation, oocysts were classified according to their size (Haug et al, 2008b), and virulence of each Eimeria spp. field isolate was assessed by lesion scoring (Johnson and Reid, 1970) following experimental infection.…”

Section: Methodsmentioning

confidence: 99%

“…Experimental infection was performed at 14 days old with 5,000 oocysts/isolate. Virulence of Eimeria filed isolates was evaluated by lesion score at six days post-challenge using a score of 0-4 according to Johnson and Reid (1970). Diet formulas contained no anticoccidial feed additives.…”

Section: Methodsmentioning

confidence: 99%

The economic impact of infection with Eimeria spp. in broiler farms from Romania

et al. 2016

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-A survey was conducted on chicken broiler farms from Romania in August-November 2010 to evaluate economic losses due to coccidiosis. Data were collected from six broiler farms of different capacity regarding chemoprophylaxis program, weight gain, feed conversion, and mortality, for two previous flocks in two houses of each farm, and finally we evaluated the economic losses. Also, faeces samples were collected and oocysts were classified according to their size, and virulence of each Eimeria spp. field isolate was determined by lesion scoring. Correlations between economic performance, oocysts category, and virulence of Eimeria were assessed by multiple linear regression. Total economic losses per 24 flocks of 18,000 chicks each were about €37,948.2, with an average of €3,162.4 per flock, and they were caused by mortality (34.8%) and poor feed conversion (65.2%). Poor body weight gain was associated with AM oocyst category (presumptively E. acervulina and/or E. mitis), high lesion score in the duodenum, and coccidiostat used for chemoprophylaxis. Feed conversion ratio was linked to the same parameters as body weight gain, minus chemoprophylaxis programme, plus total lesion score. The percentage of mortality was influenced by the lesion score in the caecum and total lesion score. Statistical analysis showed that epidemiological survey of broiler flocks during the grower period can help the farmer to avoid important economic losses due to coccidiosis. As in other countries, the economic losses caused by coccidiosis in Romania are important, and a good prophylaxis programme can reduce the economic impact of coccidiosis.

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Anticoccidial drugs: Lesion scoring techniques in battery and floor-pen experiments with chickens

Cited by 1,168 publications

References 19 publications

Biochemical parameters in Japanese quails Coturnix coturnix japonica infected with coccidia and treated with Toltrazuril

Biochemical parameters in Japanese quails Coturnix coturnix japonica infected with coccidia and treated with Toltrazuril

Anticoccidial efficacy of drinking water soluble diclazuril in the control of Eimeria acervulina oocysts on experimentally-infected broiler chickens

The economic impact of infection with Eimeria spp. in broiler farms from Romania

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