Anticoagulants in Coronary Thrombosis With Myocardial Infarction

Rytand, David A.

doi:10.1001/archinte.1951.03810080075008

Cited by 31 publications

(3 citation statements)

References 13 publications

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“…Thus it is obvious that certain basic facts regarding mortality statistics in acute coronary thrombosis with myocardial infarction require elucidation; that the status of anticoagulant therapy is still unsettled; and that new technics for more adequate study might be required to resolve the points at issue. This investigation, designed to answer several Associated serious diseases [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Diabetes . [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Congestive Failure [20][21][22][23][24][25] Uremia.…”

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confidence: 99%

“…This investigation, designed to answer several Associated serious diseases [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Diabetes . [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Congestive Failure [20][21][22][23][24][25] Uremia. [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Urinary tract infection .10 Serious Arrhythmias Emphysema.10…”

mentioning

confidence: 99%

“…[10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Congestive Failure [20][21][22][23][24][25] Uremia. [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Urinary tract infection .10 Serious Arrhythmias Emphysema.10…”

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Mortality and Other Studies Questioning the Evidence for and Value of Routine Anticoagulant Therapy in Acute Myocardial Infarction

Schnur

1953

Circulation

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This study of 1350 patients with acute myocardial infarction admitted to several hospitals during a 10-year period attempts to answer several questions currently in dispute: the correlation of the patient's condition on admission with the mortality rate, the relation of the patient's age to prognosis, and the value of routine anticoagulant therapy. It presents the major statistical objections to the study by the Committee for the Evaluation of Anticoagulants of the American Heart Association, questions the evidence upon which the Committee made its recommendations and concludes that incontrovertible proof of the advantages of routine anticoagulant therapy in patients mildly ill on admission to the hospital has not been presented thus far.

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confidence: 99%

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Mortality and Other Studies Questioning the Evidence for and Value of Routine Anticoagulant Therapy in Acute Myocardial Infarction

Schnur

1953

Circulation

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Cardiovascular Diseases

Schaaf¹

1954

AMA Arch Intern Med

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It has been hypothesized that Helicobacter pylori (Hp) infection may contribute to reduced stature, risk of hypertension or obesity. The aim was to evaluate body indices in Hp positive and negative persons. A total of 2436 subjects (4-100 years old) were tested for Hp status by 13 C-urea breath test. Data on height and weight were collected for 84%, and blood pressure for 80% of the study subjects. The prevalence of Hp infection was 41.6%. The odds ratio for a 10-year increase in age was 1.21 (95% CI 1.17-1.25, p-value <0.001). Statistically significant negative association of Hp positivity with body height was most pronounced in the younger age groups, while a positive association of Hp positivity with body mass index was only seen in those aged 15+ years. There was a negative effect of Hp positivity on systolic and diastolic blood pressure in subjects below 25 and a relatively strong positive effect on blood pressure in subjects over 65 years. Residual confounding by social characteristics as a possible explanation for the associations of Hp positivity with height and blood pressure cannot be excluded. Unmeasured factors related to social and family environment may cause the apparent association between Hp positivity and children's growth and blood pressure.

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Bishydroxycoumarin (Dicumarol) Therapy in Myocardial Infarction

Feldman¹

1954

AMA Arch Intern Med

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treatment of myocardial infarction.It was our purpose, in undertaking this study, to determine the results of anticoagulant therapy in myocardial infarction as it is carried out in a private hospital, in the daily practice of various physicians, as internists, cardiologists, and general practitioners and not by a research team. The dosage of the drug used and the prothrombin levels were adjusted by either the attending physician or the resident on his service. Hence, some kept the prothrombin levels rather low ; others, moderately low, while still others did not keep them low enough. No doubt, similar situations prevail in the daily practice in many hospitals throughout the country. We felt that a practical evaluation of anticoagulant therapy in myocardial infarction could be made more truly from such a study than from a controlled research project. Since some of the internists, cardiol-From the Department of Medicine, Mount Sinai Hospital. * References 1 and 2.t References 3-9. \s=dd\ References10 and 11. \ s=s\ References 12-21.

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Anticoagulants in Coronary Thrombosis With Myocardial Infarction

Cited by 31 publications

References 13 publications

Mortality and Other Studies Questioning the Evidence for and Value of Routine Anticoagulant Therapy in Acute Myocardial Infarction

Mortality and Other Studies Questioning the Evidence for and Value of Routine Anticoagulant Therapy in Acute Myocardial Infarction

Cardiovascular Diseases

Bishydroxycoumarin (Dicumarol) Therapy in Myocardial Infarction

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