Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry

Ntaios, George; Huisman, Menno V.; Diener, Hans-Christoph; Halperin, Jonathan L.; Teutsch, Christine; Marler, Sabrina; Gurusamy, Venkatesh Kumar; Thompson, Milla; Lip, Gregory Y. H.; Olshansky, Brian; Abban, Dzifa Wosornu; Abdul, Nasser; Abud, Atilio; Adams, Fran; Addala, Srinivas; Adragão, Pedro; Ageno, Walter; Aggarwal, Rajesh; Agosti, Sergio; Agostoni, Piergiuseppe; Aguilar, Francisco; Linares, Julio Aguilar; Aguinaga, Luis; Ahmed, Jameel; Aiello, Allessandro; Ainsworth, Paul; Aiub, Jorge Roberto; Al-Dallow, Raed; Alderson, Lisa; Velasco, Jorge Antonio Aldrete; Alexopoulos, Dimitrios; Manterola, Fernando Alfonso; Aliyar, Pareed; Alonso, David; Costa, Fernando; Amado, J. A.; Amara, W.; Amelot, Mathieu; Amjadi, Nima; Ammirati, Fabrizio; Andrade, Marianna; Andrawis, Nabil S.; Annoni, Giorgio; Ansalone, Gerardo; Ariani, M. Kevin; Arias, Juan Carlos; Armero, Sébastien; Arora, Chander; Aslam, Muhammad Shakil; Asselman, M.; Audouin, Philippe; Augenbraun, Charles; Aydın, Şenay; Ayryanova, Ivaneta; Aziz, Emad F.; Backes, Luciano Marcelo; Badings, Erik A; Bagni, E.; Baker, Seth; Bala, Richard; Baldi, Antonio; Bando, Shigenobu; Banerjee, Subhash; Bank, Alan J.; Barón-Esquivias, Gonzalo; Barr, Craig; Bartlett, Maria; Kes, Vanja Bašić; Baula, Giovanni; Behrens, Steffen; Bell, Alan; Benedetti, Raffaella; Mazuecos, Juan Benezet; Benhalima, Bouziane; Bergler‐Klein, Jutta; Berneau, Jean-Baptiste; Bernstein, Richard A.; Berrospi, Percy; Berti, Sérgio; Berz, Andrea; Best, Elizabeth; Bettencourt, Paulo; Betzu, Robert; Bhagwat, Ravi; Bhatta, Luna; Biscione, Francesco; Bisignani, Giovanni; Black, Toby; Bloch, Michael J.; Bloom, Stephen R.; Blumberg, Edwin; Bo, Mario; Bøhmer, Ellen; Bollmann, Andreas; Bongiorni, Maria Grazia; Boriani, Giuseppe; Boswijk, D.J.; Bott, Jochen; Bottacchi, E.; Kalan, Marica Bracic; Bradman, Drew; Brautigam, Donald; Breton, Nicolas; Brouwers, P. J. A. M.; Browne, Kevin F.; Cortada, Jordi Bruguera; Bruni, Adriana Antonella; Brunschwig, Claude; Buathier, Hervé; Buhl, Aurélie; Bullinga, John R.; Cabrera, Jose Walter; Caccavo, Alberto; Cai, Shanglang; Caine, Sarah; Calò, Leonardo; Calvi, Valéria; Sánchez, Mauricio Camarillo; Candeias, Rui; Capuano, Vincenzo; Capucci, Alessandro; Caputo, Ronald P.; Rizo, Tatiana Cárdenas; Cardona, Francisco; Darrieux, Francisco Carlos da Costa; Vera, Yan Carlos Duarte; Carolei, Antonio; Carreño, Susana; Carvalho, Paula; Cary, Susanna; Casu, Gavino; Cavallini, Claudio; Cayla, Guillaume; Celentano, Aldo; Cha, Tae-Joon; Soo, Kwang; Chae, Jei Keon; Chalamidas, Kathrine; Challappa, Krishnan; Chand, Sunil Prakash; Chandrashekar, Harinath; Chartier, Ludovic; Chatterjee, Kausik; Ayala, Carlos Antero Chavez; Cheema, Aamir; Cheema, Amjad; Chen, Lin; Chen, Shih‐Ann; Chen, Jyh Hong; Chiang, Fu‐Tien; Chiarella, Francesco; Chih-Chan, Lin; Cho, Yong Keun; Choi, Jong‐Il; Choi, Dong Ju; Chouinard, Guy; Chow, Danny Hoi-Fan; Chrysos, Dimitrios; Чумакова, Г. 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doi:10.1016/j.hjc.2020.11.009

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…e total SAMe-TT2R2 score was high in this study, and the corresponding threshold of the ROC curve of the obtained SAMe-TT2R2 score was 4.5 points. Currently, doctors around the world prefer to use nonvitamin K oral anticoagulants, namely new oral anticoagulants (NOACs) [17]. At the same time, some high bleeding risk parameters and elevated serum creatinine values were independent predictors of oral anticoagulant choice, resulting in inconsistency with the prediction results of the SAMe-TT2R2 score.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of ABC Bleeding Score and SAMe-TT2R2 Score on the Risk of Bleeding after Anticoagulation in Patients with Nonvalvular Atrial Fibrillation Complicated with Coronary Heart Disease

Zhang

et al. 2022

Contrast Media & Molecular Imaging

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Objective. To explore the predictive value of ABC bleeding score and SAMe-TT2R2 score on the risk of bleeding in patients with nonvalvular atrial fibrillation (NVAF) complicated with coronary heart disease (CHD) after anticoagulation. Methods. 149 patients with NVAF complicated with CHD were followed up in our hospital for one year. The bleeding events during the follow-up period were observed, the ABC bleeding score and SAMe-TT2R2 score were calculated, the predictive value of the two scoring methods for the main bleeding risk was analyzed by the ROC curve, and the AUC area under the ROC curve of the two scoring methods was compared by the Delong test. Results. There were 32 bleeding events during the follow-up period. The AUC of ABC bleeding score and SAMe-TT2R2 score were 0.775 ( P < 0.01 ) and 0.624 ( P < 0.05 ), respectively. The Delong test showed that the AUC of ABC bleeding score was significantly higher than that of SAMe-TT2R2 score (d = 2.177, P < 0.05 ). Conclusion. Both the ABC bleeding score and SAMe-TT2R2 score can predict the risk of bleeding after anticoagulation in patients with NVAF and CHD. The critical value of the SAMe-TT2R2 score for predicting bleeding events in patients with NVAF and CHD may need to be increased to 4 or 5, and the prediction ability of ABC bleeding score is significantly better than that of the SAMe-TT2R2 score.

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Section: Discussionmentioning

confidence: 99%

Evaluation of ABC Bleeding Score and SAMe-TT2R2 Score on the Risk of Bleeding after Anticoagulation in Patients with Nonvalvular Atrial Fibrillation Complicated with Coronary Heart Disease

Zhang

et al. 2022

Contrast Media & Molecular Imaging

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ANMCO-SIMEU consensus document: appropriate management of atrial fibrillation in the emergency department

Caldarola

Iaco

Pugliese

et al. 2023

European Heart Journal Supplements

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Atrial fibrillation (AF) accounts for 2% of the total presentations to the emergency department (ED) and represents the most frequent arrhythmic cause for hospitalization. It steadily increases the risk of thromboembolic events and is often associated with several comorbidities that negatively affect patient's quality of life and prognosis. AF has a considerable impact on healthcare resources, making the promotion of an adequate and coordinated management of this arrhythmia necessary in order to avoid clinical complications and to implement the adoption of appropriate technological and pharmacological treatment options. AF management varies across regions and hospitals and there is also heterogeneity in the use of anticoagulation and electric cardioversion, with limited use of direct oral anticoagulants. The ED represents the first access point for early management of patients with AF. The appropriate management of this arrhythmia in the acute setting has a great impact on improving patient's quality of life and outcomes as well as on rationalization of the financial resources related to the clinical course of AF. Therefore, physicians should provide a well-structured clinical and diagnostic pathway for patients with AF who are admitted to the ED. This should be based on a tight and propositional collaboration among several specialists, i.e. the ED physician, cardiologist, internal medicine physician, anesthesiologist. The aim of this ANMCO-SIMEU consensus document is to provide shared recommendations for promoting an integrated, accurate, and up-to-date management of patients with AF admitted to the ED or Cardiology Department, in order to make it homogeneous across the national territory.

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Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry

Cited by 2 publications

References 16 publications

Evaluation of ABC Bleeding Score and SAMe-TT2R2 Score on the Risk of Bleeding after Anticoagulation in Patients with Nonvalvular Atrial Fibrillation Complicated with Coronary Heart Disease

Evaluation of ABC Bleeding Score and SAMe-TT2R2 Score on the Risk of Bleeding after Anticoagulation in Patients with Nonvalvular Atrial Fibrillation Complicated with Coronary Heart Disease

ANMCO-SIMEU consensus document: appropriate management of atrial fibrillation in the emergency department

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