Anticholinergic drugs and anaesthesia

Mirakhur, R. K.

doi:10.1007/bf03026887

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…Low doses of romifidine (5 µg kg −1 ) appeared to have less pronounced cardiovascular effects than low doses of medetomidine, despite similar levels of sedation (Pypendop & Verstegen 2001). Anticholinergic premedication has also been recommended with α 2 ‐agonists to prevent bradyarrhythmias and, potentially, the reduction in cardiac output produced by these agents (Mirakhur 1988). However, the anticholinergic‐induced increase in heart rate does not ensure an improvement in overall cardiac performance, and may actually potentiate α 2 ‐adrenoreceptor mediated hypertension (Dunkle et al.…”

Section: Introductionmentioning

confidence: 99%

The cardiopulmonary effects of romifidine in dogs with and without prior or concurrent administration of glycopyrrolate

Sinclair

McDonell

O'Grady

et al. 2002

Veterinary Anaesthesia and Analgesia

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Section: Introductionmentioning

confidence: 99%

The cardiopulmonary effects of romifidine in dogs with and without prior or concurrent administration of glycopyrrolate

Sinclair

McDonell

O'Grady

et al. 2002

Veterinary Anaesthesia and Analgesia

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Atropine-induced heart rate changes: a comparison between midazolam-fentanyl-propofol-N2O and midazolam-fentanyl-thiopentone-enflurane-N2O anaesthesia

1990

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Atropine-induced heart rate (HR) changes were studied in 19 patients (ASA physical status I) during anaesthesia maintained predominantly with propofol-N20 or thiopentone-enflurane-N20. Ten patients (Group A) received midazolam (0.07 rag. kg-J ), fentanyl (1 Izg. kg-l ), propofol (2 mg" kg -l ) and succinylcholine (1 rag. kg-1). Following tracheal intubation, anaesthesia was maintained with propofol (6 mg. kg -I . hr-l ) (minute vol. 85 ml. kg-l ; tidal vol. 7 ml. kg-l ). Ten minutes after tracheal intubation, incremental doses of atropine (equivalent cumulative doses: 1.8, 3.6, 7.2, 14.4, (vol. minute 85 ml. kg-l ; volume courant 7 ml. kg-I ). Dix minutes aprds l' intubation, des doses croissantes d'atropine (doses cumulatives: 1,8, 3,6, 7,2, 14,4, 28,8 lzg" kg -I)

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