Anticariogenic Effect of a Sodium Monofluorophosphate Solution in Children after 21 Months of Use

Abstract

SYNOPSIS IN INTERLINGUA EFFECTO ANTICARIOGENE DE UN SOLUTION DE MONOFLUOROPHOSPHATO DE NATRIUM IN JUVENILES POST CURSOS DE APPLICATION DE VINTI-UN MENSES.—Un gruppo de 263 juveniles de etates de inter 6 e 14 annos e habitante un area a aqua fluorurate esseva dividite in duo gruppos de 129 e 134 individuos. Le juveniles in gruppo I continuava lor usual methodo de brossar lor dentes supplementate per le uso, un vice per die, de un solution de 6 pro cento de fluoruro in un preparation a aroma e a coloration rosa. Le subjectos in gruppo II recipeva le mesme instructiones, sed le solution in lor caso esseva chloruro de natrium. Le conclusiones del studio es basate super 77 juveniles usante fluoruro e 75 usante chloruro. Es presentate plur indices reflectente le plus favorabile resultatos obtenite in gruppo I. In gruppo II le reversiones esseva 66 pro cento plus frequente que in gruppo I.

The Reaction of Monofluorophosphate with Apatite

“…This was followed by other clinical studies, e.g. Finn and Jamison [1963], Goaz et al [1966], with encouraging results.…”

Caries-Preventive Fluoride Mouthrinses

“…Amine fluoride and monofluorophosphate (MFP) mouth-rinsing trials do not seem to have been performed. Good caries inhibition (52°/o) by daily toothbrushing with a MFP solution (7500 ppm F) in a fluoridated area [29] indicates clinical test ing of MFP rinses.…”

Fluoride Deposition in Enamel from Monofluorophosphate Application

“…ies inhibition has resulted from repeated ap plication of MFP solutions to the teeth of children living in an area with a fluoride-de ficient water supply [Hawes et al, 1954] and children living in an area supplied with fluoridated water [Goaz et al, 1966].…”

“…The effects of variation in solution concentration were assessed since the concentration has varied greatly in clinical trials. Hawes et al [1954] used a 15°/o solution of sodium MFP (1.04 M) while Goaz et al [1966] used a 6% solution (0.44 M). Dentifrices are usual ly prepared to contain about 1,000 ppm F. The effect of different acidities of the treat ment solutions was also investigated be cause greater fluoride deposition is seen from solutions of increased acidity [e.g.…”